CAS 1232030-35-1

Pyrido[2,3-d]pyrimidin-7(8H)-one,6-(2,4-dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]-

Description:

Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(2,4-dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]- is a complex organic compound characterized by its multi-ring structure, which includes a pyrido-pyrimidine core. This compound features various functional groups, including a dichlorophenyl moiety and a piperazinyl group, contributing to its potential biological activity. The presence of fluorine and chlorine atoms suggests that it may exhibit unique electronic properties, which can influence its reactivity and interaction with biological targets. Typically, such compounds are investigated for their pharmacological properties, including potential applications in medicinal chemistry, particularly in the development of therapeutic agents. The specific arrangement of substituents on the core structure can significantly affect the compound's solubility, stability, and overall efficacy. As with many synthetic organic compounds, safety and handling precautions are essential due to potential toxicity or reactivity. Further studies, including in vitro and in vivo evaluations, would be necessary to fully understand its biological implications and therapeutic potential.

Pyrido[2,3-d]pyriMidin-7(8H)-one, 6-(2,4-dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]aMino]-

CAS: 1232030-35-1

Formula: C₂₅H₂₃Cl₂FN₆O

Purity: %

Color and Shape: Solid

Molecular weight: 513.3941

Ref: IN-DA000K5V

FRAX486

CAS: 1232030-35-1

FRAX486

Purity: ≥98%

Molecular weight: 513.39g/mol

Ref: 54-BUP02176

6-(2,4-Dichlorophenyl)-8-Ethyl-2-((3-Fluoro-4-(Piperazin-1-Yl)Phenyl)Amino)Pyrido[2,3-D]Pyrimidin-7(8H)-One

CAS: 1232030-35-1

6-(2,4-Dichlorophenyl)-8-Ethyl-2-((3-Fluoro-4-(Piperazin-1-Yl)Phenyl)Amino)Pyrido[2,3-D]Pyrimidin-7(8H)-One

Purity: 98+%

Molecular weight: 513.39g/mol

Ref: 54-PC108735

FRAX486

CAS: 1232030-35-1

FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.

Formula: C₂₅H₂₃Cl₂FN₆O

Purity: 98.81% - 99.52%

Color and Shape: Solid

Molecular weight: 513.39

Ref: TM-T6840

FRAX486

CAS: 1232030-35-1

Purity: 98+%

Molecular weight: 513.4000244

Ref: 10-F797085

FRAX486

CAS: 1232030-35-1

FRAX486 is a kinase inhibitor that binds to the ATP-binding site of the epidermal growth factor receptor (EGFR) and prevents it from binding to ATP. The EGFR is involved in signaling pathways that are important for cell proliferation, differentiation, and survival. FRAX486 is selective for EGFR over other members of the tyrosine kinase family, such as CDK4/6. This drug has been shown to inhibit tumor growth by inducing apoptosis in mutant melanoma cells and inhibiting their migration. It also inhibits the phosphorylation of actin filaments and reduces bladder inflammation.

Formula: C₂₅H₂₃Cl₂FN₆O

Purity: Min. 95%

Molecular weight: 513.4 g/mol

Ref: 3D-HZB03035