CAS 1232416-25-9

3-[3-[4-[(Methylamino)methyl]phenyl]-5-isoxazolyl]-5-[4-[(1-methylethyl)sulfonyl]phenyl]-2-pyrazinamine

Description:

The chemical substance known as 3-[3-[4-[(Methylamino)methyl]phenyl]-5-isoxazolyl]-5-[4-[(1-methylethyl)sulfonyl]phenyl]-2-pyrazinamine, with the CAS number 1232416-25-9, is a complex organic compound characterized by its multi-ring structure and various functional groups. It features a pyrazinamine core, which is a bicyclic compound containing nitrogen atoms, contributing to its potential biological activity. The presence of isoxazole and sulfonyl groups indicates that this compound may exhibit unique chemical reactivity and solubility properties. The methylamino and isopropyl substituents suggest that it may interact with biological targets, potentially influencing its pharmacological profile. Such compounds are often investigated for their therapeutic potential in various fields, including oncology and neurology. The specific arrangement of substituents can significantly affect the compound's efficacy, selectivity, and overall behavior in biological systems. Further studies, including synthesis, characterization, and biological evaluation, would be necessary to fully understand its properties and potential applications.

Formula: C₂₄H₂₅N₅O₃S

Synonyms:

• Vx970
• Ve-822

2-Pyrazinamine, 3-[3-[4-[(methylamino)methyl]phenyl]-5-isoxazolyl]-5-[4-[(1-methylethyl)sulfonyl]phenyl]-

CAS: 1232416-25-9

Formula: C₂₄H₂₅N₅O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 463.5520

Ref: IN-DA000K80

Berzosertib

CAS: 1232416-25-9

Berzosertib

Purity: ≥95%

Molecular weight: 463.55g/mol

Ref: 54-BUP15191

Berzosertib

CAS: 1232416-25-9

Formula: C₂₄H₂₅N₅O₃S

Molecular weight: 463.17

Ref: 7W-GP9685

Berzosertib

CAS: 1232416-25-9

Berzosertib (VE-822) is an ATR inhibitor (Ki<0.2 nM) that also inhibits ATM (Ki=34 nM). Berzosertib has antitumor activity. Cost-effective and quality-assured.

Formula: C₂₄H₂₅N₅O₃S

Purity: 97.34% - >99.99%

Color and Shape: Solid

Molecular weight: 463.55

Ref: TM-T2669

VE 822

CAS: 1232416-25-9

VE 822 is a potent and selective inhibitor of ATR protein kinase, which is derived through chemical synthesis with a high specificity for ATR over related kinases. ATR, or ataxia telangiectasia and Rad3-related kinase, plays a critical role in the cellular response to DNA damage and replication stress. VE 822 achieves its mode of action by interfering with ATR’s catalytic activity, thereby halting the DNA damage response and rendering cancer cells more susceptible to DNA-damaging agents.

Formula: C₂₄H₂₅N₅O₃S

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 463.55 g/mol

Ref: 3D-FV137734