CAS 123246-29-7

ganirelix

Description:

Ganirelix is a synthetic peptide that functions as a gonadotropin-releasing hormone (GnRH) antagonist. It is primarily used in assisted reproductive technology to prevent premature ovulation during controlled ovarian stimulation. The substance is characterized by its ability to competitively inhibit the action of GnRH at the pituitary gland, thereby reducing the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This mechanism helps in controlling the timing of ovulation, which is crucial for successful fertility treatments. Ganirelix is typically administered via subcutaneous injection and is known for its relatively short half-life, necessitating careful dosing schedules. The compound is generally well-tolerated, though some patients may experience side effects such as injection site reactions or hormonal fluctuations. Its chemical structure includes a sequence of amino acids that contribute to its biological activity and specificity for the GnRH receptor. Overall, ganirelix plays a significant role in reproductive medicine, aiding in the management of fertility treatments.

Formula: C₈₀H₁₁₃ClN₁₈O₁₃

InChI: InChI=1/C80H113ClN18O13/c1-9-84-79(85-10-2)88-39-17-15-27-60(70(104)94-62(42-49(5)6)71(105)93-61(28-16-18-40-89-80(86-11-3)87-12-4)78(112)99-41-21-29-68(99)77(111)90-50(7)69(82)103)92-72(106)63(44-53-32-36-58(102)37-33-53)97-76(110)67(48-100)98-74(108)65(45-54-22-20-38-83-47-54)96-73(107)64(43-52-30-34-57(81)35-31-52)95-75(109)66(91-51(8)101)46-56-25-19-24-55-23-13-14-26-59(55)56/h13-14,19-20,22-26,30-38,47,49-50,60-68,100,102H,9-12,15-18,21,27-29,39-46,48H2,1-8H3,(H2,82,103)(H,90,111)(H,91,101)(H,92,106)(H,93,105)(H,94,104)(H,95,109)(H,96,107)(H,97,110)(H,98,108)(H2,84,85,88)(H2,86,87,89)/t50-,60-,61+,62+,63+,64-,65-,66-,67+,68+/m1/s1

Synonyms:

• N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-D-alaninamide
• Orgalutran
• Rs 26306

Ganirelix acetate

CAS: 123246-29-7

Formula: C₈₀H₁₁₃N₁₈O₁₃Cl

Purity: 95%~99%

Color and Shape: White to Off-white Powder

Molecular weight: 1570.4

Ref: BP-BPPG030

Ganirelix Acetate

CAS: 123246-29-7

Ganirelix Acetate is a gonadotropin-releasing hormone (GnRH) receptor antagonist

Formula: C₈₂H₁₁₇ClN₁₈O₁₅

Purity: 96.05%

Color and Shape: Solid

Molecular weight: 1630.4

Ref: TM-TP2337