CAS 1233339-22-4

(3R)-4-[2-(3H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)pyrimidin-4-yl]-3-methylmorpholine

Description:

The chemical substance known as (3R)-4-[2-(3H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)pyrimidin-4-yl]-3-methylmorpholine, with the CAS number 1233339-22-4, is a complex organic compound characterized by its unique structural features. It contains a morpholine ring, which is a six-membered ring containing one nitrogen atom, and is substituted with a pyrimidine and an indole moiety. The presence of a methylsulfonyl group attached to a cyclopropyl ring adds to its chemical diversity and potential reactivity. This compound is likely to exhibit specific biological activities due to its intricate structure, which may interact with various biological targets. Its stereochemistry, indicated by the (3R) designation, suggests that it has a specific three-dimensional arrangement that could influence its pharmacological properties. Such compounds are often investigated for their potential therapeutic applications, particularly in fields like medicinal chemistry and drug development, where understanding the relationship between structure and activity is crucial.

Synonyms:

• AZ20
• 4-[4-[(3R)-3-Methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl]-1H-indole
• 1H-Indole, 4-[4-[(3R)-3-methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl]-
• (R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine

1H-Indole, 4-[4-[(3R)-3-methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl]-

CAS: 1233339-22-4

Formula: C₂₁H₂₄N₄O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 412.5053

Ref: IN-DA000KDB

AZ20

CAS: 1233339-22-4

AZ20

Purity: ≥98%

Molecular weight: 412.51g/mol

Ref: 54-BUP09703

AZ20

CAS: 1233339-22-4

AZ20 is an effective and specific inhibitor of ATR kinase (IC50: 5 nM, in a cell-free assay), 8-fold selectivity over mTOR.

Formula: C₂₁H₂₄N₄O₃S

Purity: 98% - 99.69%

Color and Shape: Solid

Molecular weight: 412.51

Ref: TM-T1958

AZ20

CAS: 1233339-22-4

Purity: 98%

Molecular weight: 412.5100098

Ref: 10-F861592

AZ20

CAS: 1233339-22-4

AZ20 is a monoclonal antibody that targets the cell surface receptor stem cell factor. It has been shown to induce apoptosis in colorectal adenocarcinoma cells and prostate cancer cells, as well as to inhibit the proliferation of tumor cells in vivo. AZ20 binds to the stem cell factor receptor on the surface of cancer cells and initiates an intracellular signaling cascade that leads to the activation of caspases, resulting in programmed cell death. AZ20 also inhibits the proliferation of tumor cells by blocking their ability to bind to other cells via cell-to-cell contact. This drug has been shown to have no significant side effects on healthy tissue or immune system function.

Formula: C₂₁H₂₄N₄O₃S

Purity: Min. 95%

Molecular weight: 412.51 g/mol

Ref: 3D-IZB33922