CAS 123337-89-3

brain natriuretic peptide-45 rat

Description:

Brain natriuretic peptide-45 (BNP-45) in rats is a peptide hormone primarily involved in cardiovascular regulation. It is produced by the cardiac ventricles in response to increased myocardial wall stress, typically associated with heart failure. BNP-45 plays a crucial role in promoting natriuresis, diuresis, and vasodilation, thereby helping to reduce blood volume and pressure. The peptide is part of a larger precursor molecule, proBNP, which is cleaved to release BNP and its inactive fragment. The biological activity of BNP-45 is mediated through its interaction with specific receptors, leading to various physiological effects, including the inhibition of the renin-angiotensin-aldosterone system. In clinical settings, BNP levels are often measured as a biomarker for heart failure diagnosis and management. The CAS number 123337-89-3 uniquely identifies this specific peptide, facilitating its study and application in research and therapeutic contexts. Overall, BNP-45 is significant in understanding cardiac function and developing treatments for heart-related conditions.

Formula: C₂₁₃H₃₄₉N₇₁O₆₅S₃

Synonyms:

• H-Ser-Gln-Asp-Ser-Ala-Phe-Arg-Ile-Gln-Glu-Arg-Leu-Arg-Asn-Ser-Lys-Met-Ala-His-Ser-Ser-Ser-Cys-Phe-Gly-Gln-Lys-Ile-Asp-Arg-Ile-Gly-Ala-Val-Ser-Arg-Leu-Gly-Cys-Asp-Gly-Leu-Arg-Leu-Phe-OH (Disulfide bond)
• Bnp-45 (Rat)

L-Phenylalanine, L-seryl-L-glutaminyl-L-α-aspartyl-L-seryl-L-alanyl-L-phenylalanyl-L-arginyl-L-isoleucyl-L-glutaminyl-L-α-glutamyl-L-arginyl-L-leucyl-L-arginyl-L-asparaginyl-L-seryl-L-lysyl-L-methionyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanylglycyl-L-glutaminyl-L-lysyl-L-isoleucyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-alanyl-L-valyl-L-seryl-L-arginyl-L-leucylglycyl-L-cysteinyl-L-α-aspartylglycyl-L-leucyl-L-arginyl-L-leucyl-, cyclic (23→39)-disulfide

CAS: 123337-89-3

Purity: 98%

Color and Shape: Solid

Molecular weight: G/Mol

Ref: IN-DA000KE4

Brain Natriuretic Peptide-45, rat

CAS: 123337-89-3

BNP-45 (rat) is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency.

Formula: C₂₁₃H₃₄₉N₇₁O₆₅S₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 5040.67

Ref: TM-TP1207

BNP-45 (Rat)

CAS: 123337-89-3

BNP-45 is a peptide that binds to the beta-subunit of the Na+/K+ ATPase, inhibiting its activity. It is a potent inhibitor of the enzyme and has been used in research as a tool to study ion channels and receptor activation.
BNP-45 has been shown to inhibit ion-channel activity by binding to the beta subunit of the Na+/K+ ATPase. This inhibition leads to an increase in intracellular sodium and calcium levels, which may result in a variety of physiological effects.

Formula: C₂₁₃H₃₄₉N₇₁O₆₅S₃

Purity: Min. 95%

Molecular weight: 5,040.7 g/mol

Ref: 3D-PBN-4218-S

BNP-32 (Rat)

CAS: 123337-89-3

BNP-32 is a peptide that is an activator of the B2 receptor. It has been shown to inhibit the ion channels in cells, which may be due to its binding to the ligand-binding site on the receptor. BNP-32 has also been shown to bind to antibodies and can be used as a research tool for cell biology or other areas of life science. BNP-32 is a high purity product with CAS No. 123337-89-3.

Formula: C₁₄₆H₂₃₉N₄₇O₄₄S₃

Purity: Min. 95%

Molecular weight: 3,452.9 g/mol

Ref: 3D-PBN-4213-V

BNP-45 (rat) trifluoroacetate salt

CAS: 123337-89-3

Please enquire for more information about BNP-45 (rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₁₃H₃₄₉N₇₁O₆₅S₃

Purity: Min. 95%

Molecular weight: 5,040.69 g/mol

Ref: 3D-FB110270