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CAS 1233389-15-5

:

Daptomycin, 1-[N-(8-methyl-1-oxononyl)-L-tryptophan]-

Description:
Daptomycin, specifically the compound identified as "1-[N-(8-methyl-1-oxononyl)-L-tryptophan]-" with the CAS number 1233389-15-5, is a cyclic lipopeptide antibiotic. It is primarily used in the treatment of serious infections caused by Gram-positive bacteria, including those resistant to other antibiotics. The structure of daptomycin features a unique lipid tail that facilitates its insertion into bacterial membranes, leading to membrane depolarization and ultimately cell death. This compound exhibits a broad spectrum of activity against various pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). Daptomycin's mechanism of action is distinct from traditional antibiotics, as it disrupts bacterial cell membrane integrity rather than inhibiting cell wall synthesis. It is typically administered intravenously and is known for its favorable pharmacokinetic profile, although it may be associated with certain side effects, such as muscle toxicity. Overall, daptomycin represents a significant advancement in the treatment of multidrug-resistant bacterial infections.
Formula:C72H101N17O26
Synonyms:
  • Daptomycin, 1-[N-(8-methyl-1-oxononyl)-L-tryptophan]-
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