CAS 1234015-54-3

5-(5-(2-(3-aMinopropoxy)-6-Methoxyphenyl)-1H-pyrazol-3-ylaMino)pyrazine-2-carbonitrile hydrochloride

CAS: 1234015-54-3

Formula: C₁₈H₂₁Cl₂N₇O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 438.3110

Ref: IN-DA009CIX

Prexasertib dihydrochloride

CAS: 1234015-54-3

Prexasertib dihydrochloride

Purity: ≥95%

Molecular weight: 438.31g/mol

Ref: 54-BUP12915

Prexasertib dihydrochloride

CAS: 1234015-54-3

Prexasertib dihydrochloride (LY2606368) inhibits CHK1 (Ki: 0.9 nM); IC50: CHK2 8 nM, RSK 9 nM.

Formula: C₁₈H₂₁Cl₂N₇O₂

Purity: 98.46% - 99.82%

Color and Shape: Solid

Molecular weight: 438.31

Ref: TM-T4327

Prexasertib dihydrochloride

CAS: 1234015-54-3

Purity: 99%

Molecular weight: 437.113

Ref: 10-F979112

Prexasertib HCl (LY2606368)

CAS: 1234015-54-3

LY2606368 is a monoclonal antibody that binds to the death protein and prevents it from activating other proteins that promote cell growth. It has been shown to be effective in treating pediatric patients with metastatic pancreatic cancer. LY2606368 is a potent inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase, which is associated with tumorigenesis. Prexasertib has been shown to induce cell lysis and apoptosis by inhibiting the Bcl-2 family of proteins, which regulate mitochondrial membrane permeability. This drug also inhibits phosphatidylinositol 3-kinases (PI3Ks) and cyclooxygenases, which are involved in tumorigenesis.

Formula: C₁₈H₁₉N₇O₂·2HCl

Purity: Min. 95%

Molecular weight: 438.31 g/mol

Ref: 3D-JZB01554