CAS 1234015-58-7

Prexasertib dimesylate

CAS: 1234015-58-7

Prexasertib dimesylate is a selective CHK1 inhibitor with K i 0.9 nM, blocks CHK2 & RSK1, induces DNA breakage, and has potent anti-tumor effects.

Formula: C₂₀H₂₇N₇O₈S₂

Color and Shape: Solid

Molecular weight: 557.6

Ref: TM-T38620

Prexasertib (dimesylate)

CAS: 1234015-58-7

Prexasertib (dimesylate) is a peptide that functions as an inhibitor of receptor tyrosine kinases. It blocks the activation of these receptors by binding to the ATP-binding pocket, thereby inhibiting their downstream signaling. Prexasertib binds with high affinity and specificity to the ATP-binding pocket of EGFR, HER2/neu, and PDGFRα receptors. This drug also prevents ligands from binding to these receptors, which may cause cancer cell proliferation.

Formula: C₂₀H₂₇N₇O₈S₂

Purity: Min. 95%

Molecular weight: 557.6 g/mol

Ref: 3D-JZB01558