CAS 123441-03-2

Rivastigmine

Description:

Rivastigmine is a reversible inhibitor of the enzyme acetylcholinesterase, primarily used in the treatment of Alzheimer's disease and Parkinson's disease dementia. It enhances cholinergic neurotransmission by preventing the breakdown of acetylcholine, a neurotransmitter crucial for memory and learning. Rivastigmine is characterized by its chemical formula, which includes elements such as carbon, hydrogen, nitrogen, and oxygen, reflecting its complex structure. The substance is typically administered in the form of capsules or transdermal patches, allowing for flexible dosing and improved patient compliance. Its pharmacokinetics indicate that it is absorbed relatively quickly, with peak plasma concentrations occurring within a few hours after administration. Rivastigmine is known for its side effects, which may include nausea, vomiting, diarrhea, and insomnia, necessitating careful monitoring of patients. Additionally, it has a relatively short half-life, requiring multiple daily doses or continuous delivery via patches to maintain therapeutic levels. Overall, Rivastigmine plays a significant role in managing cognitive symptoms associated with neurodegenerative diseases.

Formula: C₁₄H₂₂N₂O₂

InChI: InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1

InChI key: InChIKey=XSVMFMHYUFZWBK-NSHDSACASA-N

SMILES: O(C(N(CC)C)=O)C1=CC([C@@H](N(C)C)C)=CC=C1

Synonyms:

• 3-((1S)-1-(Dimethylamino)ethyl)phenyl N-ethyl-N-methylcarbamate
• 3-[(1S)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate
• 3-[1-(Dimethylamino)Ethyl]Phenyl Ethyl(Methyl)Carbamate
• Carbamic acid, N-ethyl-N-methyl-, 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester
• Carbamic acid, ethylmethyl-, 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester
• Carbamic acid, ethylmethyl-, 3-[1-(dimethylamino)ethyl]phenyl ester, (S)-
• ENA 713 free base
• Ethylmethylcarbamic acid 3-((1S)-1-(dimethylamino)ethyl)phenyl ester
• Exelon
• Nimvastid
• Prometax
• Rivastach
• Rivastigimine(Forr&Donly)
• Rivastigmine Base
• S-Rivastigmine
• Sdz 212-713

Rivastigmine L-Tartrate

CAS: 123441-03-2, 129101-54-8

Formula: C₁₄H₂₂N₂O₂·C₄H₆O₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 400.43

Ref: 3B-R0093

Rivastigmine

CAS: 123441-03-2

Formula: C₁₄H₂₂N₂O₂

Purity: >98.0%(HPLC)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 250.34

Ref: 3B-R0250

Rivastigmine

CAS: 123441-03-2

Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereof

Formula: C₁₄H₂₂N₂O₂

Color and Shape: Yellow Clear Liquid Viscous

Molecular weight: 250.16813

Ref: 45-1604836

Rivastigmine

CAS: 123441-03-2

Rivastigmine (Exelon) is a Cholinesterase Inhibitor, used for therapy of Alzheimer disease.

Formula: C₁₄H₂₂N₂O₂

Purity: 99.45%

Color and Shape: Solid

Molecular weight: 250.34

Ref: TM-T0229

3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate

CAS: 123441-03-2

Formula: C₁₄H₂₂N₂O₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 250.3367

Ref: IN-DA000KLF

Rivastigmine

CAS: 123441-03-2

Rivastigmine

Purity: 99%

Molecular weight: 250.34g/mol

Ref: 54-OR1027342

Rivastigmine

CAS: 123441-03-2

Rivastigmine

Purity: ≥98%

Molecular weight: 250.34g/mol

Ref: 54-BUP14165

Rivastigmine

CAS: 123441-03-2

Formula: C₁₄H₂₂N₂O₂

Purity: ≥ 98.0%

Color and Shape: Colourless to light-yellow liquid

Molecular weight: 250.34

Ref: 7W-GP0564

Rivastigmine

Controlled Product

CAS: 123441-03-2

Formula: C₁₄H₂₂N₂O₂

Color and Shape: Colourless

Molecular weight: 250.34

Ref: 04-C16815350

(S)-Rivastigmine-d4

Controlled Product

CAS: 123441-03-2

Applications Rivastigmine-d4 is an intermediate in the synthesis of Rivastigmine-d4 Tartrate Salt (R541004), the labeled analogue of Rivastigmine Tartrate Salt (R541000), a brain selective acetylcholinesterase inhibitor. Nootropic.
References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),

Formula: C₁₄H₁₈D₄N₂O₂

Color and Shape: Colourless

Molecular weight: 254.36

Ref: TR-R541007

Rivastigmine

CAS: 123441-03-2

Formula: C₁₄H₂₂N₂O₂

Purity: 95%

Color and Shape: Liquid, Viscous

Molecular weight: 250.342

Ref: 10-F462714

Rivastigmine

Controlled Product

CAS: 123441-03-2

Acetylcholinesterase and butyrylcholinesterase inhibitor

Formula: C₁₄H₂₂N₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 250.34 g/mol

Ref: 3D-FR15397

(S)-Rivastigmine

CAS: 123441-03-2

Applications S-Rivastigmine is an isomer of Rivastigmine ( an acetylcholinesterase inhibitor used in the treatment of neurological disorders such as Alzheimer’s disease.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Howes, L et al.: Drug. Safe., 37, 391 (2014); Shahar, O. et al.: Nucl. Acids Res., 42, 5869 (2014);

Formula: C₁₄H₂₂N₂O₂

Color and Shape: Colourless

Molecular weight: 250.34

Ref: TR-R540995