CAS 123441-03-2: Rivastigmine
Description:Rivastigmine is a reversible inhibitor of the enzyme acetylcholinesterase, primarily used in the treatment of Alzheimer's disease and Parkinson's disease dementia. It enhances cholinergic neurotransmission by preventing the breakdown of acetylcholine, a neurotransmitter crucial for memory and learning. Rivastigmine is characterized by its chemical formula, which includes elements such as carbon, hydrogen, nitrogen, and oxygen, reflecting its complex structure. The substance is typically administered in the form of capsules or transdermal patches, allowing for flexible dosing and improved patient compliance. Its pharmacokinetics indicate that it is absorbed relatively quickly, with peak plasma concentrations occurring within a few hours after administration. Rivastigmine is known for its side effects, which may include nausea, vomiting, diarrhea, and insomnia, necessitating careful monitoring of patients. Additionally, it has a relatively short half-life, requiring multiple daily doses or continuous delivery via patches to maintain therapeutic levels. Overall, Rivastigmine plays a significant role in managing cognitive symptoms associated with neurodegenerative diseases.
Formula:C14H22N2O2
InChI:InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1
InChI key:InChIKey=XSVMFMHYUFZWBK-NSHDSACASA-N
SMILES:O=C(OC1=CC=CC(=C1)C(N(C)C)C)N(C)CC
- Synonyms:
- 3-((1S)-1-(Dimethylamino)ethyl)phenyl N-ethyl-N-methylcarbamate
- 3-[(1S)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate
- 3-[1-(Dimethylamino)Ethyl]Phenyl Ethyl(Methyl)Carbamate
- Carbamic acid, N-ethyl-N-methyl-, 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester
- Carbamic acid, ethylmethyl-, 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester
- Carbamic acid, ethylmethyl-, 3-[1-(dimethylamino)ethyl]phenyl ester, (S)-
- ENA 713 free base
- Ethylmethylcarbamic acid 3-((1S)-1-(dimethylamino)ethyl)phenyl ester
- Exelon
- Nimvastid
- See more synonyms
- Prometax
- Rivastach
- Rivastigimine(Forr&Donly)
- Rivastigmine Base
- S-Rivastigmine
- Sdz 212-713
- Rivastigmine