CAS 123447-62-1: Prulifloxacin

Description:Prulifloxacin is a synthetic fluoroquinolone antibiotic, primarily used for the treatment of bacterial infections. It exhibits broad-spectrum antibacterial activity, particularly against Gram-negative and some Gram-positive bacteria. The compound functions by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. Prulifloxacin is characterized by its relatively high oral bioavailability and is often administered in its prodrug form, which is converted into its active metabolite in the body. This antibiotic is known for its favorable pharmacokinetic properties, including a moderate half-life, allowing for once-daily dosing in many cases. Additionally, it has been noted for its lower propensity to cause certain side effects commonly associated with other fluoroquinolones, such as tendon damage. However, like all antibiotics, its use should be guided by susceptibility patterns to minimize the risk of resistance development. Overall, Prulifloxacin represents a valuable option in the antibiotic arsenal, particularly for treating urinary tract infections and other susceptible bacterial infections.

Formula:C₂₁H₂₀FN₃O₆S

InChI:InChI=1S/C21H20FN3O6S/c1-10-16(31-21(29)30-10)9-23-3-5-24(6-4-23)15-8-14-12(7-13(15)22)18(26)17(20(27)28)19-25(14)11(2)32-19/h7-8,11H,3-6,9H2,1-2H3,(H,27,28)

InChI key:InChIKey=PWNMXPDKBYZCOO-UHFFFAOYSA-N

SMILES:O=C1OC(=C(O1)CN2CCN(C=3C=C4C(=CC3F)C(=O)C(C(=O)O)=C5SC(N54)C)CC2)C

Synonyms:
(+/-)-7-{4-[(Z)-2,3-Dihydroxy-2-Butenyl]-1-Piperazinyl}-6-Fluoro-1-Methyl-4-Oxo-1H,4H-[1,3]Thiazeto[3,2-A]Quinoline-3-Carboxylic Acid Cyclic Carbonate
(1R)-6-fluoro-1-methyl-7-{4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]piperazin-1-yl}-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid
1,3-Dioxole, 1H,4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid deriv.
1H,4H-[1,3]Thiazeto[3,2-a]quinoline-3-carboxylic acid, 6-fluoro-1-methyl-7-[4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]-1-piperazinyl]-4-oxo-
6-Fluoro-1-Methyl-7-(4-(5-Methyl-2-Oxo-1,3-Dioxelen-4-Yl)Methyl-1-Piperazinyl)-4-Oxo-4H-(1,3)Thiazeto(3,2-A)Quinoline-3-Carboxylic Acid
6-Fluoro-1-methyl-7-[4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]-1-piperazinyl]-4-oxo-1H,4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid
6-fluoro-1-methyl-7-[4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]piperazin-1-yl]-4-oxo-2a,3-dihydro-1H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid
6-fluoro-1-methyl-7-{4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]piperazin-1-yl}-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid
Nm 441
Quisnon
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Found 10 products.

Product data	Purity	Price range	Estimated delivery
1H,4H-[1,3]Thiazeto[3,2-a]quinoline-3-carboxylic acid, 6-fluoro-1-methyl-7-[4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]-1-piperazinyl]-4-oxo- REF: IN-DA000KL9CAS: 123447-62-1	98%	To inquire	Tue 06 May 25
Prulifloxacin REF: 54-BUP17215CAS: 123447-62-1	≥98%	98.00 €~1,134.00 €	Mon 05 May 25
Prulifloxacin REF: 4Z-P-421CAS: 123447-62-1	- - -	To inquire	Mon 05 May 25
Prulifloxacin REF: 7W-GA1815CAS: 123447-62-1	- - -	To inquire	Mon 05 May 25
Prulifloxacin REF: 54-PC109254CAS: 123447-62-1	98%	32.00 €~2,035.00 €	Mon 05 May 25
Prulifloxacin-d8 REF: 4Z-P-422CAS: 123447-62-1	- - -	To inquire	Mon 05 May 25
Prulifloxacin REF: 3B-P2058CAS: 123447-62-1	>98.0%(T)(HPLC)	90.00 €~350.00 €	Wed 07 May 25
Prulifloxacin REF: TM-T5394CAS: 123447-62-1	99.47%	48.00 €~171.00 €	Tue 13 May 25
Prulifloxacin REF: TR-P838885CAS: 123447-62-1	- - -	105.00 €~255.00 €	Wed 14 May 25
Prulifloxacin REF: 3D-AP27249CAS: 123447-62-1	Min. 95%	147.00 €~856.00 €	Thu 15 May 25