CAS 123464-89-1

Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-, hydrochloride (1:1)

Description:

Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-, hydrochloride (1:1) is a chemical compound characterized by its unique bicyclic structure, which includes a nitrogen atom within a bicyclic framework. This compound features a benzamide moiety, indicating the presence of a benzene ring attached to a carbonyl group (C=O) linked to an amine. The "4-chloro" designation indicates the presence of a chlorine atom at the fourth position of the benzamide structure, which can influence its reactivity and biological activity. The hydrochloride form suggests that the compound is a salt, enhancing its solubility in water and stability. This compound may exhibit pharmacological properties, potentially acting as a ligand or inhibitor in various biological systems. Its stereochemistry, denoted by the (3R) configuration, implies specific spatial arrangements that can affect its interaction with biological targets. Overall, this compound's characteristics make it of interest in medicinal chemistry and drug development, particularly in the context of its potential therapeutic applications.

Formula: C₁₄H₁₇ClN₂O·ClH

InChI: InChI=1S/C14H17ClN2O.ClH/c15-12-3-1-11(2-4-12)14(18)16-13-9-17-7-5-10(13)6-8-17;/h1-4,10,13H,5-9H2,(H,16,18);1H/t13-;/m0./s1

InChI key: InChIKey=HSEQUIRZHDYOIX-ZOWNYOTGSA-N

SMILES: N(C(=O)C1=CC=C(Cl)C=C1)[C@@H]2C3(CCN(C2)CC3)[H].Cl

Synonyms:

• (R)-4-Chloro-N-(quinuclidin-3-yl)benzamide hydrochloride
• Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-, hydrochloride (1:1)
• Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-, monohydrochloride
• Benzamide, N-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-, monohydrochloride, (R)-
• Pnu 282987

Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-, hydrochloride (1:1)

CAS: 123464-89-1

Formula: C₁₄H₁₈Cl₂N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 301.2115

Ref: IN-DA000KO7

(R)-4-Chloro-N-(Quinuclidin-3-Yl)Benzamide Hydrochloride

CAS: 123464-89-1

(R)-4-Chloro-N-(Quinuclidin-3-Yl)Benzamide Hydrochloride

Purity: 98%

Molecular weight: 301.21g/mol

Ref: 54-OR1008517

PNU-282987

CAS: 123464-89-1

PNU-282987

Purity: ≥98%

Molecular weight: 301.21g/mol

Ref: 54-BUP15516

PNU-282987

CAS: 123464-89-1

PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; no affinity for α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM).

Formula: C₁₄H₁₈Cl₂N₂O

Purity: 99% - >99.99%

Color and Shape: Solid

Molecular weight: 301.21

Ref: TM-T2422

PNU 282987

CAS: 123464-89-1

Agonist of ?7 nicotinic acetylcholine receptor

Formula: C₁₄H₁₇ClN₂O·HCl

Purity: Min. 95%

Molecular weight: 301.21 g/mol

Ref: 3D-BP162687