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CAS 123482-22-4

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Zatosetron

Description:
Zatosetron is a chemical compound classified as a selective serotonin receptor antagonist, specifically targeting the 5-HT3 receptor. It is primarily investigated for its potential therapeutic applications in managing gastrointestinal disorders, particularly in alleviating symptoms associated with nausea and vomiting. The compound's mechanism of action involves blocking serotonin's effects at the 5-HT3 receptors, which are located in the central nervous system and the gastrointestinal tract. This action helps to reduce the sensation of nausea and the urge to vomit. Zatosetron is characterized by its specific molecular structure, which contributes to its pharmacological properties. While it has shown promise in clinical settings, further research is necessary to fully understand its efficacy, safety profile, and potential side effects. As with many pharmacological agents, the development and approval processes are crucial for determining its therapeutic viability and market availability.
Formula:C19H25ClN2O2
InChI:InChI=1/C19H25ClN2O2/c1-19(2)10-11-6-12(20)7-16(17(11)24-19)18(23)21-13-8-14-4-5-15(9-13)22(14)3/h6-7,13-15H,4-5,8-10H2,1-3H3,(H,21,23)/t13-,14+,15-
InChI key:InChIKey=SPKBYQZELVEOLL-QDMKHBRRNA-N
SMILES:C(N[C@H]1C[C@@]2(N(C)[C@](C1)(CC2)[H])[H])(=O)C3=C4C(CC(C)(C)O4)=CC(Cl)=C3
Synonyms:
  • 5-Chloro-2,3-dihydro-2,2-dimethyl-N-[(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-7-benzofurancarboxamide
  • 7-Benzofurancarboxamide, 5-chloro-2,3-dihydro-2,2-dimethyl-N-[(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-
  • LY 277359
  • Zatosetron
  • 7-Benzofurancarboxamide, 5-chloro-2,3-dihydro-2,2-dimethyl-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-, endo-
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