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CAS 1235141-39-5

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15S-5,6-trans-Latanprost

Description:
15S-5,6-trans-Latanprost, identified by its CAS number 1235141-39-5, is a synthetic prostaglandin analog primarily used in ophthalmology for the treatment of glaucoma and ocular hypertension. This compound functions as a selective agonist for the prostaglandin F2α receptor, promoting increased outflow of aqueous humor, which helps to lower intraocular pressure. Its structural characteristics include a trans configuration at the 5 and 6 positions, which is crucial for its biological activity. The compound is typically administered as an eye drop formulation and is known for its efficacy and relatively favorable side effect profile. Common side effects may include conjunctival hyperemia, increased eyelash growth, and changes in iris pigmentation. The pharmacokinetics of 15S-5,6-trans-Latanprost involve rapid absorption and metabolism, leading to its active form, which exerts the therapeutic effects. Overall, this compound represents a significant advancement in the management of glaucoma, providing a valuable option for patients requiring long-term treatment.
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