CAS 1235318-89-4

2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-

Description:

2-Pyrimidinamine, 4-methyl-N-[5-methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]- is a chemical compound characterized by its complex structure, which includes a pyrimidine ring, a thiazole moiety, and a pyrazole group. This compound typically exhibits properties associated with heterocyclic compounds, such as potential biological activity due to the presence of nitrogen-containing rings. It may demonstrate solubility in polar solvents, and its reactivity can be influenced by the functional groups present, particularly the amine and thiazole functionalities. The compound's molecular structure suggests potential applications in medicinal chemistry, possibly as a pharmaceutical agent or in agrochemical formulations. Its specific interactions, stability, and reactivity would depend on the surrounding environment, including pH and temperature. As with many heterocycles, it may also exhibit interesting electronic properties, making it a subject of interest in material science and organic synthesis. Safety and handling precautions should be observed, as with any chemical substance, particularly those with biological activity.

Formula: C₁₂H₁₂N₆S

Synonyms:

• ADX-88178
• ADX88178
• 2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-
• 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-amine
• 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine
• ADX88178, >98%
• ADX-88178;ADX 88178;ADX88178
• 4-methyl-N-[5-methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-2-Pyrimidinamine

2-Pyrimidinamine, 4-methyl-N-[5-methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-

CAS: 1235318-89-4

Formula: C₁₂H₁₂N₆S

Purity: 95%

Color and Shape: Solid

Molecular weight: 272.3289

Ref: IN-DA000KQL

ADX88178

CAS: 1235318-89-4

ADX88178

Purity: ≥98%

Molecular weight: 272.33g/mol

Ref: 54-BUP10085

ADX88178

CAS: 1235318-89-4

ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.

Formula: C₁₂H₁₂N₆S

Purity: 99.55%

Color and Shape: Solid

Molecular weight: 272.33

Ref: TM-T4500

ADX88178

CAS: 1235318-89-4

ADX88178 is a novel enantiomer of L-glutamic acid, which is currently being studied for its potential as an antidepressant drug. ADX88178 has been shown to produce locomotor effects in mice, and also has anti-inflammatory mechanisms. The drug binds to the 5-membered heteroaryl site on the glutamate receptor, which is not present in humans. This binding leads to increased serotonin levels in the brain and reduced inflammation, both of which are linked to depression and other psychiatric disorders. Preliminary studies have shown that ADX88178 may be effective against autoimmune diseases such as multiple sclerosis, as well as cancer.

Formula: C₁₂H₁₂N₆S

Purity: Min. 95%

Molecular weight: 272.33 g/mol

Ref: 3D-KZB31889