CAS 123536-14-1

(R)-(+)-3-Aminoquinuclidine dihydrochloride

Description:

(R)-(+)-3-Aminoquinuclidine dihydrochloride is a chiral organic compound characterized by its quinuclidine structure, which features a bicyclic framework. This compound is a derivative of quinuclidine, possessing an amino group at the 3-position, which contributes to its basicity and potential for forming salts, such as the dihydrochloride form. It is typically a white to off-white crystalline solid, soluble in water and polar organic solvents, making it suitable for various applications in medicinal chemistry and pharmacology. The presence of the amino group allows for interactions with biological targets, potentially influencing neurotransmitter systems. Its chirality is significant, as the (R)-enantiomer may exhibit different pharmacological properties compared to its (S)-counterpart. As a dihydrochloride salt, it is often used in research settings for its stability and ease of handling. Overall, (R)-(+)-3-Aminoquinuclidine dihydrochloride is of interest in the development of therapeutic agents, particularly in the context of neurological disorders.

Formula: C₇H₁₄N₂·2ClH

InChI: InChI=1S/C7H14N2.2ClH/c8-7-5-9-3-1-6(7)2-4-9;;/h6-7H,1-5,8H2;2*1H/t7-;;/m0../s1

InChI key: InChIKey=STZHBULOYDCZET-KLXURFKVSA-N

SMILES: N[C@@H]1C2CCN(C1)CC2.Cl

Synonyms:

• (3R)-1-azabicyclo[2.2.2]octan-3-amine
• (3R)-3-Aminoquinuclidine dihydrochloride
• (3R)-Quinuclidin-3-Amine Dihydrochloride
• (R) 3-Aminoquinuclidine Hydrochloride
• (R)-(+)-3-Aminoquinuclidine Dihydrochloride
• (R)-(+)-3-Aminoquinuclidine diHCl
• (R)-(+)-3-Aminoquinuclidine dihydrochlorid
• (R)-(+)-3-Aminoquinuclidine2HCl
• (R)-1-Azabicyclo[2,2,2]Octan-3-Amine Dihydrochloride
• (R)-Quinuclidin-3-amine dihydrochloride
• 1-Azabicyclo[2.2.2]octan-3-amine, dihydrochloride, (3R)-
• 1-Azabicyclo[2.2.2]octan-3-amine, dihydrochloride, (R)-
• 1-Azabicyclo[2.2.2]octan-3-amine, hydrochloride (1:2), (3R)-
• 1-azabicyclo[2,2,2]octan-3-amine,dihydrochloride,(R)-

(R)-(+)-3-Aminoquinuclidine Dihydrochloride

CAS: 123536-14-1

Formula: C₇H₁₄N₂·2HCl

Purity: >98.0%(T)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 199.12

Ref: 3B-A2830

(R)-(+)-3-Aminoquinuclidine DiHCl

CAS: 123536-14-1

Formula: C₇H₁₆Cl₂N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 199.1213

Ref: IN-DA000KQO

(3R)-3-Aminoquinuclidine dihydrochloride

CAS: 123536-14-1

(3R)-3-Aminoquinuclidine dihydrochloride

Formula: C₇H₁₄N₂·2ClH

Purity: 97%

Color and Shape: faint yellow crystalline solid

Molecular weight: 199.12g/mol

Ref: 54-OR6142

(3R)-Quinuclidin-3-amine dihydrochloride

CAS: 123536-14-1

Formula: C₇H₁₆Cl₂N₂

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 199.12

Ref: 10-F065013

(R)-(+)-3-Aminoquinuclidine Dihydrochloride

CAS: 123536-14-1

Formula: C₇H₁₄N₂·2HCl

Color and Shape: White To Off-White Solid

Molecular weight: 126.20 2*36.46

Ref: 4Z-P-5332

(3R)-Aminoquinuclidine Dihydrochloride

Controlled Product

CAS: 123536-14-1

Stability Hygroscopic
Applications (3R)-Aminoquinuclidine is used in the preparation of serotonin type 3 (5-HT3) receptor antagonist as potential new drugs for the treatment of irritable bowel syndrome (IBS).
References Manning, D.D. et al.: Bioorg. Med. Chem. Lett., 21, 58 (2011); Langlois, M. et al.: Eur. J. Med. Chem., 29, 925 (1994);

Formula: C₇H₁₄N₂·2ClH

Color and Shape: Neat

Molecular weight: 199.12

Ref: TR-A629195

(R)-(+)-3-Aminoquinuclidine dihydrochloride

CAS: 123536-14-1

A building block; used for synthesis tryptophan 2,?3-?dioxygenase inhibitors

Formula: C₇H₁₄N₂•(HCl)₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 199.12 g/mol

Ref: 3D-FA04240

(R)-3-Aminoquinuclidine dihydrochloride

CAS: 123536-14-1

3-Aminoquinuclidine dihydrochloride is a high quality, reagent, complex compound that can be used as a useful intermediate to produce other fine chemicals. The CAS number for this compound is 123536-14-1. 3-Aminoquinuclidine dihydrochloride is a fine chemical that has many uses in the production of research chemicals and speciality chemicals. This compound can be used as a versatile building block in synthesis reactions and as a reaction component.

Formula: C₇H₁₆Cl₂N₂

Purity: Min. 97 Area-%

Molecular weight: 199.12 g/mol

Ref: 3D-Q-100108