CAS 1235406-03-7

Benzenesulfonamide, 5-chloro-2-fluoro-4-[2-(4-pyridazinyl)-4-(trifluoromethyl)phenoxy]-N-1,3,4-thiadiazol-2-yl-

CAS: 1235406-03-7

Formula: C₁₉H₁₀ClF₄N₅O₃S₂

Purity: 95%

Molecular weight: 531.891

Ref: IN-DA000KRI

PF-05186462

CAS: 1235406-03-7

PF-05186462

Purity: ≥98%

Molecular weight: 531.89g/mol

Ref: 54-BUP00893

PF-05186462

CAS: 1235406-03-7

PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.

Formula: C₁₉H₁₀ClF₄N₅O₃S₂

Purity: 99.10% - 99.37%

Color and Shape: Solid

Molecular weight: 531.89

Ref: TM-T8711

PF-05186462

CAS: 1235406-03-7

PF-05186462 is a potent, selective and orally bioavailable small molecule inhibitor of the enzyme protein tyrosine phosphatase 1B (PTP1B). This enzyme is required for the activation of many downstream signaling pathways. PF-05186462 is being investigated for its potential as a therapeutic agent for treatment of diseases such as type 2 diabetes, Alzheimer's disease, and cancer.

Formula: C₁₉H₁₀ClF₄N₅O₃S₂

Purity: Min. 95%

Molecular weight: 531.9 g/mol

Ref: 3D-KZB40603