CAS 1235440-45-5

Imidazo[1,2-a]pyridine, 6,8-dichloro-2-(chloromethyl)-, hydrochloride (1:1)

Description:

Imidazo[1,2-a]pyridine, 6,8-dichloro-2-(chloromethyl)-, hydrochloride (1:1) is a chemical compound characterized by its imidazo-pyridine structure, which incorporates both imidazole and pyridine rings. This compound features dichloro substitutions at the 6 and 8 positions of the imidazo ring, along with a chloromethyl group at the 2 position, contributing to its reactivity and potential biological activity. The hydrochloride form indicates that the compound is a salt, which enhances its solubility in water and may influence its pharmacokinetic properties. Typically, compounds of this nature are studied for their potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to their ability to interact with biological targets. The presence of chlorine atoms can also affect the compound's lipophilicity and overall stability. As with many heterocyclic compounds, the specific arrangement of atoms and functional groups plays a crucial role in determining its chemical behavior and potential uses in various fields, including drug development and agrochemicals.

Formula: C₈H₅Cl₃N₂·ClH

InChI: InChI=1S/C8H5Cl3N2.ClH/c9-2-6-4-13-3-5(10)1-7(11)8(13)12-6;/h1,3-4H,2H2;1H

InChI key: InChIKey=FFDINBXPZXZKPB-UHFFFAOYSA-N

SMILES: ClC=1C=2N(C=C(CCl)N2)C=C(Cl)C1.Cl

Synonyms:

• Imidazo[1,2-a]pyridine, 6,8-dichloro-2-(chloromethyl)-, hydrochloride (1:1)

6,8-Dichloro-2-(chloromethyl)imidazo[1,2-a]pyridine hydrochloride

CAS: 1235440-45-5

6,8-Dichloro-2-(chloromethyl)imidazo[1,2-a]pyridine hydrochloride (6,8DCI) is a compound that has been shown to inhibit the activity of cyclooxygenase-2 (COX-2) and dpp-iv. The rate constant for 6,8DCI was determined using electrochemical impedance spectroscopy experiments on a solution of 6,8DCI in acetonitrile. It has also been shown to be effective against cell factor and human serum albumin. The optimum concentration for 6,8DCI is found to be 1 mM when it is used with an optical sensor.

Formula: C₈H₆Cl₄N₂

Purity: Min. 95%

Molecular weight: 272 g/mol

Ref: 3D-KZB44045