CAS 123562-20-9

endothelin 2

Description:

Endothelin-2 (ET-2) is a peptide that plays a significant role in various physiological processes, particularly in the cardiovascular system. It is part of the endothelin family, which includes endothelin-1 and endothelin-3, and is produced primarily by endothelial cells. ET-2 is known for its potent vasoconstrictive properties, meaning it can cause blood vessels to narrow, thereby influencing blood pressure and flow. The peptide is composed of 21 amino acids and is characterized by its ability to bind to specific endothelin receptors (ET_A and ET_B), which mediate its biological effects. In addition to its role in vascular regulation, endothelin-2 is involved in cellular proliferation, inflammation, and various pathophysiological conditions, including heart failure and pulmonary hypertension. Its synthesis and release can be stimulated by various factors, including hypoxia and inflammatory cytokines. Understanding the characteristics and functions of endothelin-2 is crucial for developing therapeutic strategies targeting cardiovascular diseases and other related disorders.

Formula: C₁₁₅H₁₆₀N₂₆O₃₂S₄

Synonyms:

• H-Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Oh

Endothelin-2 (human, canine)

CAS: 123562-20-9

ET-2 (human, canine)

Formula: C₁₁₅H₁₆₀N₂₆O₃₂S₄

Purity: 96.8%

Color and Shape: White Powder

Molecular weight: 2546.96

Ref: 01-4016278

Endothelin-2 (49-69), human

CAS: 123562-20-9

Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.

Formula: C₁₁₅H₁₆₀N₂₆O₃₂S₄

Purity: 98.26%

Color and Shape: Solid

Molecular weight: 2546.92

Ref: TM-TP1174

Endothelin-2 (human, canine)

CAS: 123562-20-9

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₁₁₅H₁₆₀N₂₆O₃₂S₄

Molecular weight: 2,546.97 g/mol

Ref: 3D-PP50517

Endothelin 2 (human, canine)

CAS: 123562-20-9

Custom research peptide; min purity 95%.

Formula: C₁₁₅H₁₆₀N₂₆O₃₂S₄

Purity: Min. 95%

Molecular weight: 2,546.97 g/mol

Ref: 3D-PE16958

Endothelin-2 (Human)

CAS: 123562-20-9

Endothelin-2 (ET-2) and Endothelin-1 (ET-1) differ from each other by 2 amino acids and have affinity for ETA and ETB G-protein coupled receptors which are found in a variety of tissues, including lungs, heart, kidneys, uterus and vasculature. It is believed that ET-2 is a potent vasoconstrictor and may play a role in cancer, immunology and heart failure.
This product has disulfide bonds between Cys1-Cys and Cys3-Cys11, is of Canine source and is available as a 0.1mg vial.

Formula: C₁₁₅H₁₆₀N₂₆O₃₂S₄

Purity: Min. 95%

Molecular weight: 2,546.9 g/mol

Ref: 3D-PED-4209-S

Endothelin-2 (human, canine) acetate

CAS: 123562-20-9

Acetate salt

Formula: C₁₁₅H₁₆₀N₂₆O₃₂S₄

Purity: Min. 95%

Molecular weight: 2,546.92 g/mol

Ref: 3D-FE110370

Endothelin-2 (human, canine) trifluoroacetate

CAS: 123562-20-9

Trifluoroacetate salt

Formula: C₁₁₅H₁₆₀N₂₆O₃₂S₄

Purity: Min. 95%

Molecular weight: 2,546.92 g/mol

Ref: 3D-FE110255