CAS 1236033-03-6

1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-[7-(hydroxyMethyl)-7H-pyrrolo[2,3-d]pyriMidin-4-yl]-,(βR)-

Description:

1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-[7-(hydroxymethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-, (βR)- is a complex organic compound characterized by its unique structural features, including a pyrazole ring and a pyrrolopyrimidine moiety. This compound exhibits a range of chemical properties typical of heterocyclic compounds, such as potential reactivity due to the presence of functional groups like the nitrile and hydroxymethyl groups. Its stereochemistry, indicated by the (βR) designation, suggests specific spatial arrangements that may influence its biological activity and interactions. The presence of the cyclopentyl group contributes to its hydrophobic characteristics, which can affect solubility and permeability in biological systems. This compound may be of interest in medicinal chemistry, particularly for its potential pharmacological applications, as compounds with similar structures often exhibit significant biological activity. However, detailed studies on its specific properties, including solubility, stability, and biological effects, would be necessary to fully understand its potential uses and mechanisms of action.

Formula: C₁₈H₂₀N₆O

Synonyms:

• Ruxolitinib N-Methanol
• (3R)-3-cyclopentyl-3-[4-[7-(hydroxymethyl)pyrrolo[2,3-d]pyrimidin-4-yl]pyrazol-1-yl]propanenitrile
• Ruxolitinib Impurity 4
• 1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-[7-(hydroxyMethyl)-7H-pyrrolo[2,3-d]pyriMidin-4-yl]-,(βR)-

Ruxolitinib Impurity 10

CAS: 1236033-03-6, 2743427-60-1

Formula: C₁₈H₂₀N₆O

Molecular weight: 336.40

Ref: 4Z-R-093014

Ruxolitinib Impurity 57

CAS: 1236033-03-6

Formula: C₁₈H₂₀N₆O

Molecular weight: 336.40

Ref: 4Z-R-093076

Ruxolitinib N-Methanol

Controlled Product

CAS: 1236033-03-6

Applications Ruxolitinib N-Methanol is an impurity of Ruxolitinib. Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.
References Shilling, A.D. et al.: Drug Metab. Disp., 38, 2023 (2010); Mesa, R.A.: IDrugs, 13, 394 (2010); Campas-Moya, C.: Drugs Fut., 35, 457 (2010);

Formula: C₁₈H₂₀N₆O

Color and Shape: Neat

Molecular weight: 336.391

Ref: TR-R701990

Ruxolitinib N-Methanol

CAS: 1236033-03-6

Formula: C₁₈H₂₀N₆O

Molecular weight: 336.4

Ref: ST-EA-CP-R53022