CAS 123663-49-0: Iguratimod

Description: Iguratimod is a synthetic small molecule classified as an immunomodulator, primarily used in the treatment of rheumatoid arthritis. Its chemical structure features a unique combination of functional groups that contribute to its pharmacological activity. Iguratimod works by inhibiting the production of pro-inflammatory cytokines and modulating immune responses, which helps to reduce inflammation and joint damage associated with autoimmune conditions. The substance is known for its relatively favorable safety profile compared to traditional disease-modifying antirheumatic drugs (DMARDs). In terms of solubility, Iguratimod is generally soluble in organic solvents but has limited solubility in water, which can affect its bioavailability. The compound is typically administered orally and is metabolized in the liver, with its pharmacokinetics influenced by various factors, including dosage and individual patient characteristics. Overall, Iguratimod represents a valuable option in the therapeutic landscape for managing chronic inflammatory diseases.

Formula: C₁₇H₁₄N₂O₆S

InChI: InChI=1S/C17H14N2O6S/c1-26(22,23)19-13-8-15-12(17(21)14(9-24-15)18-10-20)7-16(13)25-11-5-3-2-4-6-11/h2-10,19H,1H3,(H,18,20)

InChI key: InChIKey=ANMATWQYLIFGOK-UHFFFAOYSA-N

SMILES: O=CNC1=COC=2C=C(NS(=O)(=O)C)C(OC=3C=CC=CC3)=CC2C1=O

Synonyms:

• 3-Formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one
• Ailamode
• Careram
• Kolbet
• Methanesulfonamide, N-[3-(formylamino)-4-oxo-6-phenoxy-4H-1-benzopyran-7-yl]-
• N-[3-(Formylamino)-4-oxo-6-phenoxy-4H-1-benzopyran-7-yl]methanesulfonamide
• N-[3-(formylamino)-4-oxo-6-phenoxy-4H-chromen-7-yl]methanesulfonamide
• N-[7-methanesulfonamido-4-oxo-6-(phenoxy)chromen-3-yl]formamide
• T 614
• T 614 (antiinflammatory)
• iguratimod( R&D)
• Iguratimod

Methanesulfonamide, N-[3-(formylamino)-4-oxo-6-phenoxy-4H-1-benzopyran-7-yl]-

CAS: 123663-49-0

• Formula: C₁₇H₁₄N₂O₆S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 374.3679

Iguratimod

CAS: 123663-49-0

• Formula: C₁₇H₁₄N₂O₆S
• Color and Shape: White To Off-White Solid
• Molecular weight: 374.37

N-(7-(Methylsulfonamido)-4-Oxo-6-Phenoxy-4H-Chromen-3-Yl)Formamide

CAS: 123663-49-0

• Purity: 0.99
• Molecular weight: 374.37g/mol

Iguratimod

CAS: 123663-49-0

• Formula: C₁₇H₁₄N₂O₆S
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 374.37

Iguratimod

CAS: 123663-49-0

Iguratimod (T614) is a COX-2 inhibitor (IC50: 20 μM), does not affect COX-1, and inhibits …

• Formula: C₁₇H₁₄N₂O₆S
• Purity: 99.96%
• Color and Shape: White Powder
• Molecular weight: 374.37

N-(7-(Methylsulfonamido)-4-oxo-6-phenoxy-4H-chromen-3-yl)formamide

CAS: 123663-49-0

• Purity: 95.0%
• Molecular weight: 374.3699951171875

Iguratimod

CAS: 123663-49-0

Positive regulator of NF-κB and RANKL; anti-rheumatic; anti-inflammatory

• Formula: C₁₇H₁₄N₂O₆S
• Purity: Min. 95%
• Color and Shape: White Clear Liquid
• Molecular weight: 374.37 g/mol

Iguratimod - Bio-X ™

CAS: 123663-49-0

Iguratimod is a drug that is used to treat autoimmune and inflammatory conditions such as …

• Formula: C₁₇H₁₄N₂O₆S
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 374.37 g/mol

Iguratimod-d5

CAS: 123663-49-0

• Formula: C₁₇D₅H₉N₂O₆S
• Color and Shape: Neat
• Molecular weight: 379.399

Iguratimod

CAS: 123663-49-0

Applications Iguratimod acts as an anti-inflammatory agent, used primarily in the treatment of rheumatoid arthritis. …

• Formula: C₁₇H₁₄N₂O₆S
• Color and Shape: Neat
• Molecular weight: 374.37