CAS 123931-40-8

11,12-Eet

Description:

11,12-Eet, also known as 11,12-epoxyeicosatrienoic acid, is a bioactive lipid derived from arachidonic acid, which plays a significant role in various physiological processes. This compound is characterized by its epoxide functional group, which contributes to its reactivity and biological activity. It is primarily involved in the regulation of vascular tone and has been implicated in the modulation of inflammation and pain pathways. 11,12-Eet is known to interact with specific receptors and enzymes, influencing cellular signaling and promoting vasodilation. Its presence in biological systems is often associated with cardiovascular health, and it may have therapeutic potential in treating conditions related to vascular dysfunction. The compound is typically studied in the context of its metabolic pathways and effects on endothelial cells, making it a subject of interest in pharmacological and biomedical research. As with many eicosanoids, its stability and reactivity can be influenced by environmental factors, which are important considerations in experimental settings.

Formula: C₂₀H₃₂O₃

InChI: InChI=1S/C20H32O3/c1-2-3-4-5-9-12-15-18-19(23-18)16-13-10-7-6-8-11-14-17-20(21)22/h6,8-10,12-13,18-19H,2-5,7,11,14-17H2,1H3,(H,21,22)/b8-6-,12-9-,13-10-/t18-,19+/m1/s1

InChI key: InChIKey=DXOYQVHGIODESM-LZXKBWHHSA-N

SMILES: C(/C=C\C/C=C\CCCC(O)=O)[C@H]1[C@@H](C/C=C\CCCCC)O1

Synonyms:

• 5,8-Decadienoic acid, 10-[(2S,3R)-3-(2Z)-2-octen-1-yl-2-oxiranyl]-, (5Z,8Z)-
• 11,12-Epoxy-(5Z,8Z,14Z)-eicosatrienoic acid ~100 mug/mL in ethanol, >=95%

11,12-Epoxy-(5Z,8Z,14Z)-eicosatrienoic acid

CAS: 123931-40-8

Formula: C₂₀H₃₂O₃

Molecular weight: 320.47

Ref: 7W-GK5735

(±)11(12)-EET

CAS: 123931-40-8

(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3[]A higher

Formula: C₂₀H₃₂O₃

Color and Shape: Solid

Molecular weight: 320.47

Ref: TM-T35494

11,(12)-epoxy-5(Z),8(Z),14(Z)-eicosatrienoic acid

CAS: 123931-40-8

Formula: C20H32O3

Purity: >95%

Color and Shape: In solution, Ethanol

Molecular weight: 320.47

Ref: 48-12-2033

14(15)-Epoxy-5Z,8Z,11Z-eicosatrienoic Acid-D11

Controlled Product

CAS: 123931-40-8

Formula: C₂₀D₁₁H₂₁O₃

Color and Shape: Neat

Molecular weight: 331.534

Ref: TR-E350672

11,12-EET

CAS: 123931-40-8

11,12-EET is an analog of the human protein that has been found to have potential medicinal benefits in the treatment of cancer. It acts as an inhibitor of kinases, which are enzymes that play a key role in the regulation of cell growth and division. 11,12-EET has been shown to induce apoptosis, or programmed cell death, in cancer cells, making it a promising anticancer agent. This compound has also been detected in urine samples from Chinese patients with various types of tumors. Ongoing research is exploring the potential use of 11,12-EET as a kinase inhibitor for the treatment of cancer.

Formula: C₂₀H₃₂O₃

Purity: Min. 95%

Molecular weight: 320.5 g/mol

Ref: 3D-YEA93140