CAS 123940-54-5: Hypocrellin B

Description: Hypocrellin B is a natural compound classified as a perylenequinone, primarily derived from the fungus Hypocrea lixii. It exhibits a distinctive dark red to purple color and is known for its photosensitizing properties, making it of interest in photodynamic therapy (PDT) for cancer treatment. The compound has a complex molecular structure characterized by multiple fused aromatic rings, contributing to its strong light absorption in the visible spectrum. Hypocrellin B is soluble in organic solvents but has limited solubility in water, which can influence its bioavailability and therapeutic application. In addition to its potential in cancer therapy, it has shown antimicrobial and antiviral activities, further expanding its relevance in medicinal chemistry. The compound's mechanism of action involves the generation of reactive oxygen species upon light activation, leading to cellular damage in targeted tissues. Overall, Hypocrellin B represents a promising candidate in the field of photomedicine, with ongoing research aimed at optimizing its efficacy and safety for clinical use.

Formula: C₃₀H₂₄O₉

InChI: InChI=1S/C30H24O9/c1-10-7-12-18-23-19(27(34)29(12)38-5)13(32)8-15(36-3)21(23)22-16(37-4)9-14(33)20-25(22)24(18)26(17(10)11(2)31)30(39-6)28(20)35/h8-9,32-33H,7H2,1-6H3

InChI key: InChIKey=APTUSGMALOMQQL-UHFFFAOYSA-N

SMILES: O=C1C(OC)=C2C=3C=4C1=C(O)C=C(OC)C4C=5C(OC)=CC(O)=C6C(=O)C(OC)=C(C3C65)CC(=C2C(=O)C)C

Synonyms:

• 1H-Cyclohepta[ghi]perylene-5,12-dione, 3-acetyl-6,11-dihydroxy-4,8,9,13-tetramethoxy-2-methyl-
• 3-Acetyl-6,11-dihydroxy-4,8,9,13-tetramethoxy-2-methyl-1H-cyclohepta[ghi]perylene-5,12-dione
• 6-acetyl-8,9-dihydroxy-3,7,11,12-tetramethoxy-5-methyl-1H-cyclohepta[ghi]perylene-1,2(4H)-dione
• Hc-B
• Hypocrelin B
• Hypocrellin B, Hypocrella Bambusae
• Hypocrellin B

HYPOCRELLIN B

CAS: 123940-54-5

• Formula: C₃₀H₂₄O₉
• Purity: 98%
• Molecular weight: 528.5062

Hypocrellin B

CAS: 123940-54-5

• Formula: C₃₀H₂₄O₉
• Molecular weight: 528.51

Hypocrellin B

CAS: 123940-54-5

Hypocrellin B has sonodynamic action to induce mitochondrial damage, survival inhibition, apoptosis and inhibit adhesion …

• Formula: C₃₀H₂₄O₉
• Purity: 95%~99%
• Molecular weight: 528.513

HYPOCRELLIN B

CAS: 123940-54-5

HYPOCRELLIN B, from Hypocrella bambusae, breaks DNA, triggers apoptosis in ovarian cells, and stops Staphylococcus …

• Formula: C₃₀H₂₄O₉
• Purity: 98% - 98.87%
• Color and Shape: Solid
• Molecular weight: 528.51

Hypocrellin B

CAS: 123940-54-5

Hypocrellin B is a potent inhibitor of the activation of voltage-gated ion channels. It inhibits …

• Formula: C₃₀H₂₄O₉
• Purity: Min. 95%
• Molecular weight: 528.51 g/mol