Poloxipan, identified by its CAS number 1239513-63-3, is a synthetic polymer belonging to the class of nonionic surfactants. It is characterized by its amphiphilic nature, possessing both hydrophilic and hydrophobic segments, which allows it to effectively reduce surface tension and stabilize emulsions. Poloxipan is often used in pharmaceutical formulations, particularly as a solubilizing agent and stabilizer for various active ingredients. Its structure typically consists of a poly(ethylene oxide) and poly(propylene oxide) block copolymer, which contributes to its versatility in different applications, including personal care products and industrial formulations. The substance is known for its biocompatibility and low toxicity, making it suitable for use in medical and cosmetic applications. Additionally, Poloxipan exhibits temperature-sensitive properties, which can influence its solubility and behavior in different environments. Overall, its unique characteristics make it a valuable component in various formulations across multiple industries.

Poloxipan

1239513-63-3: Poloxipan, identified by its CAS number 1239513-63-3, is a synthetic polymer belonging to the class of nonionic surfactants. It is characterized by its amphiphilic nature, possessing both hydrophilic and hydrophobic segments, which allows it to effectively reduce surface tension and stabilize emulsions. Poloxipan is often used in pharmaceutical formulations, particularly as a solubilizing agent and stabilizer for various active ingredients. Its structure typically consists of a poly(ethylene oxide) and poly(propylene oxide) block copolymer, which contributes to its versatility in different applications, including personal care products and industrial formulations. The substance is known for its biocompatibility and low toxicity, making it suitable for use in medical and cosmetic applications. Additionally, Poloxipan exhibits temperature-sensitive properties, which can influence its solubility and behavior in different environments. Overall, its unique characteristics make it a valuable component in various formulations across multiple industries.

Poloxipan inhibits PLK1 (IC50: 3.2µM), PLK2 (1.7µM), PLK3 (3µM); minimal effect on Chk2, STAT1, STAT5b, Lck.

CAS 1239513-63-3

Poloxipan

Poloxipan

Ref: TM-T71156