CAS 123973-25-1

2-Fluoro-3-(trifluoromethyl)aniline

Description:

2-Fluoro-3-(trifluoromethyl)aniline is an aromatic amine characterized by the presence of a fluorine atom and a trifluoromethyl group attached to a benzene ring. The molecular structure features a fluorine substituent at the second position and a trifluoromethyl group at the third position relative to the amino group. This compound is typically a colorless to pale yellow liquid or solid, depending on its physical state at room temperature. It exhibits moderate solubility in organic solvents and is less soluble in water due to its hydrophobic trifluoromethyl group. The presence of the trifluoromethyl group enhances its lipophilicity and can influence its reactivity and interaction with biological systems. As with many fluorinated compounds, it may exhibit unique electronic properties, making it of interest in various applications, including pharmaceuticals and agrochemicals. Safety precautions should be taken when handling this compound, as it may pose health risks, including potential toxicity.

Formula: C₇H₅F₄N

InChI: InChI=1/C7H5F4N/c8-6-4(7(9,10)11)2-1-3-5(6)12/h1-3H,12H2

SMILES: c1cc(c(c(c1)N)F)C(F)(F)F

Synonyms:

• 3-Amino-2-Fluorobenzotrifluoride
• Alpha,Alpha,Alpha,2-Tetrafluoro-M-Toluidine
• Buttpark 45\01-71
• 2-Fluoro-3-aminobenzotrifluoride

2-Fluoro-3-(trifluoromethyl)aniline

CAS: 123973-25-1

Formula: C₇H₅F₄N

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 179.12

Ref: 3B-F1294

Benzenamine, 2-fluoro-3-(trifluoromethyl)-

CAS: 123973-25-1

Formula: C₇H₅F₄N

Purity: 98%

Color and Shape: Liquid

Molecular weight: 179.1149

Ref: IN-DA000LAO

3-Amino-2-fluorobenzotrifluoride

CAS: 123973-25-1

3-Amino-2-fluorobenzotrifluoride

Formula: C₇H₅F₄N

Purity: 98%

Color and Shape: clear. faint yellow liquid

Molecular weight: 179.11g/mol

Ref: 54-PC1073

3-Amino-2-fluorobenzotrifluoride

CAS: 123973-25-1

Formula: C₇H₅F₄N

Purity: 98%

Color and Shape: Liquid

Molecular weight: 179.118

Ref: 10-F003128

2-Fluoro-3-(trifluoromethyl)aniline

Controlled Product

CAS: 123973-25-1

Applications 2-Fluoro-3-(trifluoromethyl)aniline is a buliding block for various inhibitors such as 5,6,7-Trimethoxy-N-phenyl(ethyl)-4-aminoquinazoline derivatives that have anticancer activities and N-[3-(Phenylcarbamoyl)aryl]pyrimidine-5-carboxamide that are lymphocyte-specific kinase inhibitors.
References Zhang, Y., et al.: Eur. J. Med. Chem., 66, 335 (2013); Deak, H., et al.: Bioorg. Med. Chem. Lett., 18, 1172 (2008)

Formula: C₇H₅F₄N

Color and Shape: Neat

Molecular weight: 179.11

Ref: TR-F595585