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CAS 1240299-33-5

:

AZD-3514

Description:
AZD-3514 is a small molecule inhibitor primarily targeting the androgen receptor (AR), which plays a crucial role in the progression of prostate cancer. It is classified as a selective androgen receptor modulator (SARM) and is designed to disrupt the signaling pathways associated with androgen receptors, thereby inhibiting tumor growth in androgen-dependent cancers. AZD-3514 has shown potential in preclinical studies for its ability to reduce AR activity and has been investigated for its therapeutic efficacy in various cancer models. The compound is characterized by its specific binding affinity to the androgen receptor, which allows it to modulate receptor activity effectively. Additionally, AZD-3514's pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are critical for its development as a therapeutic agent. Ongoing research aims to further elucidate its safety profile and effectiveness in clinical settings, particularly for patients with advanced prostate cancer who have developed resistance to conventional therapies.
Formula:C25H32F3N7O2
InChI:InChI=1S/C25H32F3N7O2/c1-18(36)33-14-12-32(13-15-33)16-17-37-21-4-2-19(3-5-21)20-8-10-34(11-9-20)23-7-6-22-29-30-24(25(26,27)28)35(22)31-23/h2-5,20H,6-17H2,1H3
InChI key:InChIKey=JMEYDSHPKCSIJC-UHFFFAOYSA-N
SMILES:C(F)(F)(F)C=1N2C(=NN1)CCC(=N2)N3CCC(CC3)C4=CC=C(OCCN5CCN(C(C)=O)CC5)C=C4
Synonyms:
  • 1-(4-(2-(4-(1-(3-(trifluoromethyl)-7,8-dihydro-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)phenoxy)ethyl)piperazin-1-yl)ethanone
  • 1-[4-[2-[4-[1-[7,8-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-b]pyridazin-6-yl]-4-piperidinyl]phenoxy]ethyl]-1-piperazinyl]-ethanone
  • 1-(4-(2-(4-(1-(3-(Trifluoromethyl)-7,8-dihydro-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-
  • AZD3514 USP/EP/BP
  • AZD3514;AZD-3514;AZD 3514
  • Ethanone, 1-[4-[2-[4-[1-[7,8-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-b]pyridazin-6-yl]-4-piperidinyl]phenoxy]ethyl]-1-piperazinyl]-
  • AZD 3514; AZD-3514
  • CS-795
  • AZD3514
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Found 4 products.