CAS 124043-51-2
:1,24-dihydroxyvitamin D2
Description:
1,24-Dihydroxyvitamin D2, also known as 1,24-dihydroxyergocalciferol, is a biologically active form of vitamin D2, which is crucial for calcium and phosphate metabolism in the body. This compound is characterized by the presence of two hydroxyl (-OH) groups, one at the 1-position and another at the 24-position of the ergocalciferol structure. It plays a significant role in regulating gene expression related to calcium homeostasis and bone health. The substance is typically synthesized in the liver and kidneys from vitamin D2, which is obtained through dietary sources or synthesized in the skin upon exposure to ultraviolet light. 1,24-Dihydroxyvitamin D2 exhibits a high affinity for the vitamin D receptor, influencing various biological processes, including immune function and cell differentiation. Its therapeutic applications include the treatment of conditions like osteoporosis and certain types of rickets. However, like other vitamin D metabolites, it must be used cautiously to avoid potential toxicity associated with excessive calcium levels.
Formula:C28H44O3
InChI:InChI=1/C28H44O3/c1-18(2)28(6,31)15-13-19(3)24-11-12-25-21(8-7-14-27(24,25)5)9-10-22-16-23(29)17-26(30)20(22)4/h9-10,13,15,18-19,23-26,29-31H,4,7-8,11-12,14,16-17H2,1-3,5-6H3/b15-13+,21-9+,22-10-/t19-,23-,24-,25?,26?,27-,28-/m1/s1
Synonyms:- 1Alpha,24(S)-Dihydroxyvitamind2
- (3R,5Z,7E,14xi,22E)-9,10-secoergosta-5,7,10,22-tetraene-1,3,24-triol
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