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CAS 124182-57-6

:

CGS 21680

Description:
CGS 21680, with the CAS number 124182-57-6, is a selective agonist for the adenosine A2A receptor, which is part of the purinergic signaling system in the body. This compound is known for its potential neuroprotective effects and is often studied in the context of neurological disorders, such as Parkinson's disease. CGS 21680 exhibits high affinity for the A2A receptor, leading to various physiological effects, including vasodilation and modulation of neurotransmitter release. Its chemical structure features a purine-like core, which is characteristic of many adenosine receptor ligands. The compound is typically administered in research settings to explore its therapeutic potential and mechanisms of action. Due to its specificity for the A2A receptor, CGS 21680 serves as a valuable tool in pharmacological studies aimed at understanding adenosine receptor signaling pathways and their implications in health and disease.
Formula:C23H29N7O6
InChI:InChI=1S/C23H29N7O6/c1-2-25-21(35)18-16(33)17(34)22(36-18)30-11-27-15-19(24)28-23(29-20(15)30)26-10-9-13-5-3-12(4-6-13)7-8-14(31)32/h3-6,11,16-18,22,33-34H,2,7-10H2,1H3,(H,25,35)(H,31,32)(H3,24,26,28,29)/t16-,17+,18-,22+/m0/s1
InChI key:InChIKey=PAOANWZGLPPROA-RQXXJAGISA-N
SMILES:O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=C(NCCC4=CC=C(CCC(O)=O)C=C4)N3)O[C@H](C(NCC)=O)[C@H]1O
Synonyms:
  • 3-[4-[2-[[6-amino-9-[(2R,3S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-tetrahydrofuran-2-yl]purin-2-yl]amino]ethyl]phenyl]propanoic acid hydrochloride
  • 4-[2-[[6-Amino-9-(N-ethyl-β-<span class="text-smallcaps">D</span>-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid
  • Benzenepropanoic acid, 4-[2-[[6-amino-9-(N-ethyl-β-<span class="text-smallcaps">D</span>-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]-
  • Cgs 21680
  • 4-[2-[[6-Amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid
  • Benzenepropanoic acid, 4-[2-[[6-amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]-
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