Perindopril-d4 Acyl-D-glucuronide is a chemical compound that serves as a metabolite of the antihypertensive drug perindopril, which is an angiotensin-converting enzyme (ACE) inhibitor. This compound is characterized by the presence of a glucuronic acid moiety, which is a common feature in the metabolism of various drugs, facilitating their excretion. The "d4" designation indicates that this compound is a deuterated form of perindopril, meaning that certain hydrogen atoms have been replaced with deuterium, a stable isotope of hydrogen. This modification can enhance the compound's stability and alter its pharmacokinetic properties. The acyl group in the name suggests that the glucuronide is formed through the conjugation of perindopril with acyl groups, which can influence its solubility and biological activity. Overall, Perindopril-d4 Acyl-D-glucuronide is significant in pharmacokinetic studies and drug metabolism research, particularly in understanding the elimination pathways of perindopril in the body.

Perindopril-d4 Acyl--D-glucuronide

1241977-12-7: Perindopril-d4 Acyl-D-glucuronide is a chemical compound that serves as a metabolite of the antihypertensive drug perindopril, which is an angiotensin-converting enzyme (ACE) inhibitor. This compound is characterized by the presence of a glucuronic acid moiety, which is a common feature in the metabolism of various drugs, facilitating their excretion. The "d4" designation indicates that this compound is a deuterated form of perindopril, meaning that certain hydrogen atoms have been replaced with deuterium, a stable isotope of hydrogen. This modification can enhance the compound's stability and alter its pharmacokinetic properties. The acyl group in the name suggests that the glucuronide is formed through the conjugation of perindopril with acyl groups, which can influence its solubility and biological activity. Overall, Perindopril-d4 Acyl-D-glucuronide is significant in pharmacokinetic studies and drug metabolism research, particularly in understanding the elimination pathways of perindopril in the body.

CAS 1241977-12-7

Perindopril-d4 Acyl--D-glucuronide