CAS 1242184-41-3

Diltiazem-d6

Description:

Diltiazem-d6 is a deuterated form of diltiazem, a calcium channel blocker primarily used in the treatment of hypertension and angina. The "d6" designation indicates that six hydrogen atoms in the diltiazem molecule have been replaced with deuterium, a stable isotope of hydrogen. This modification can enhance the compound's stability and alter its pharmacokinetic properties, making it useful in research applications, particularly in studies involving drug metabolism and pharmacodynamics. Diltiazem itself is characterized by its ability to inhibit calcium ion influx across cell membranes, leading to vasodilation and reduced heart rate. The deuterated version may exhibit differences in solubility, absorption, and distribution compared to its non-deuterated counterpart. Diltiazem-d6 is typically used in scientific research rather than clinical settings, and its unique isotopic labeling allows for advanced analytical techniques, such as mass spectrometry, to track its behavior in biological systems. As with any chemical substance, proper handling and safety protocols should be observed when working with diltiazem-d6.

Formula: C₂₂H₂₆N₂O₄S

Synonyms:

• CRD-401-d6
• Also See: D460622 and D460623
• AltiazeM-d6
• Diltiazem D6 Q: What is the storage condition of
• Diltiazem D6 Q: What are the applications of
• Diltiazem D6 Q: What is the CAS Number of
• Masdil-d6
• DilzeM-d6
• Diltiazem D6Q: What is
• [2H6]-Diltiazem
• AdizeM-d6
• Diltiazem D6
• Diltiazem-d6
• Zilden-d6
• DiltiazeM-d6

Diltiazem-d6

CAS: 1242184-41-3

Formula: C₂₂H₂₀D₆N₂O₄S

Molecular weight: 420.56

Ref: 4Z-D-0729

Diltiazem-d6

Controlled Product

CAS: 1242184-41-3

Applications Labelled Diltiazem (D460620). A calcium channel blocher with vasodilating activity. Antianginal; antihypertensive; antiarrhythmic (class IV).
References Sato, et al.: Arzneim.-Forsch., 21, 1338 (1971), Smirnov, S.R.: Eur. J. Pharmacol., 360, 81 (1998), Hansson, L., et al.: Lancet, 356, 359 (2000),

Formula: C₂₂H₂₀D₆N₂O₄S

Color and Shape: White To Light Beige

Molecular weight: 420.55

Ref: TR-D460624

Diltiazem-d6

CAS: 1242184-41-3

Diltiazem-d6 is a high purity, stable diltiazem labeled with the radioisotope carbon-11. Diltiazem-d6 is used as a research tool for studying protein interactions, receptor binding and ion channel activation. The product is also used as a ligand for mapping peptide libraries and antibody production. Diltiazem-d6 has shown to have an inhibitory effect on calcium channels in cardiac muscle cells.

Formula: C₂₂H₂₆N₂O₄S

Purity: Min. 95%

Molecular weight: 420.6 g/mol

Ref: 3D-SZB18441