CAS 124345-07-9

N-Hydroxysertraline

Description:

N-Hydroxysertraline is a chemical compound that is a derivative of sertraline, which is primarily known as an antidepressant in the selective serotonin reuptake inhibitor (SSRI) class. This compound features a hydroxylamine functional group, which contributes to its unique chemical properties. N-Hydroxysertraline is characterized by its potential role in modulating serotonin levels in the brain, similar to its parent compound. It may exhibit different pharmacological effects compared to sertraline, potentially influencing its efficacy and safety profile. The compound is typically studied in the context of its biochemical interactions and therapeutic applications, particularly in mental health disorders. Its molecular structure includes a phenyl ring, a piperazine moiety, and a hydroxylamine group, which together influence its solubility, stability, and reactivity. As with many pharmaceutical compounds, understanding its characteristics is crucial for evaluating its potential therapeutic benefits and risks. Further research is often necessary to fully elucidate its mechanisms of action and clinical relevance.

Formula: C₁₇H₁₇Cl₂NO

Synonyms:

• Sertraline N-Hydroxy
• 1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-hydroxy-N-methyl-, (1S-cis)- (9CI)
• (1S-cis)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-hydroxy-N-Methyl-1-naphthalenaMine
• N-Hydroxysertraline
• N-Hydroxy Sertraline

N-Hydroxy Sertraline

CAS: 124345-07-9

Formula: C₁₇H₁₇Cl₂NO

Color and Shape: White To Off-White Solid

Molecular weight: 322.23

Ref: 4Z-S-0331

N-Hydroxy Sertraline

CAS: 124345-07-9

Applications N-Hydroxy Sertraline is one of the major metabolite of Sertraline (S280000), a potent and selective inhibitor of neuronal serotonin uptake.
References Tremaine, L.M., et al.: Drug Metab. Dispos., 17, 542 (1989),

Formula: C₁₇H₁₇Cl₂NO

Color and Shape: Neat

Molecular weight: 384.379

Ref: TR-H953730

N-Hydroxy Sertraline

CAS: 124345-07-9

Formula: C₁₇H₁₇Cl₂NO

Molecular weight: 322.23

Ref: ST-EA-CP-S6064

N-Hydroxy sertraline

CAS: 124345-07-9

N-Hydroxy sertraline is a metabolite of the antidepressant drug, sertraline. It is formed by the action of cytochrome P450 enzymes in the liver. N-Hydroxy sertraline is not active as an antidepressant, but it may have some activity against bacterial infections. There are no pharmacopoeia standards for this compound.

Formula: C₁₇H₁₇Cl₂NO

Purity: Min. 95%

Molecular weight: 322.20 g/mol

Ref: 3D-ZEA34507