CAS 1243685-62-2

SPI--112Me

CAS: 1243685-62-2

SPI--112Me

Purity: ≥95%

Molecular weight: 482.48g/mol

Ref: 54-BUP04325

SPI--112Me

CAS: 1243685-62-2

SPI--112Me, a prodrug of SPI-112, preferentially inhibits the PTPase activity of Shp2 over Shp1 and PTP1B by more than 20-fold in cell-free assays.

Formula: C₂₃H₁₉FN₄O₅S

Purity: 96.49%

Color and Shape: Solid

Molecular weight: 482.48

Ref: TM-T4627

SPI-112Me

CAS: 1243685-62-2

SPI-112Me is an analog of interferon-alfa-2b (IFN-α). It has been shown to be activated by dephosphorylation and to bind to the epidermal growth factor receptor (EGFR) with high affinity. SPI-112Me inhibits the phosphatase activity of EGFR, leading to decreased cellular uptake and activation of the cell cycle. SPI-112Me also inhibits tumor xenografts in transgenic animals and reduces cancer cell proliferation in vivo. This compound has been found to inhibit the binding of a number of inhibitors to their targets.

Formula: C₂₃H₁₉FN₄O₅S

Purity: Min. 95%

Molecular weight: 482.49 g/mol

Ref: 3D-TZB68562