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CAS 124429-27-2

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4-chloro-8-fluoroquinazoline

Description:
4-Chloro-8-fluoroquinazoline is a heterocyclic compound belonging to the quinazoline family, characterized by a fused bicyclic structure containing a benzene ring and a pyrimidine ring. This compound features a chlorine atom at the 4-position and a fluorine atom at the 8-position of the quinazoline ring, which can influence its chemical reactivity and biological activity. Typically, quinazolines exhibit a range of pharmacological properties, including antimicrobial, anticancer, and anti-inflammatory activities, making them of interest in medicinal chemistry. The presence of halogen substituents, such as chlorine and fluorine, can enhance lipophilicity and metabolic stability, potentially improving the compound's bioavailability. Additionally, 4-chloro-8-fluoroquinazoline may serve as a valuable intermediate in the synthesis of more complex molecules or as a lead compound in drug discovery. Its specific physical and chemical properties, such as solubility, melting point, and spectral characteristics, would be determined through experimental methods and may vary based on the conditions of synthesis and purification.
Formula:C8H4ClFN2
InChI:InChI=1/C8H4ClFN2/c9-8-5-2-1-3-6(10)7(5)11-4-12-8/h1-4H
SMILES:c1cc2c(c(c1)F)ncnc2Cl
Synonyms:
  • Quinazoline, 4-Chloro-8-Fluoro-
  • 4-Chloro-8-fluoroquinazoline
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