CAS 124431-80-7

Benzenepropanoic acid,4-[2-[[6-amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]-, hydrochloride (1:1)

Description:

Benzenepropanoic acid, 4-[2-[[6-amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]-, hydrochloride (1:1), identified by CAS number 124431-80-7, is a complex organic compound characterized by its structural components that include a benzene ring, a propanoic acid moiety, and a purine derivative. The presence of the amino and ethyl groups suggests potential for hydrogen bonding and interactions with biological systems, making it of interest in pharmaceutical applications. As a hydrochloride salt, it is likely to be more soluble in water compared to its free base form, enhancing its bioavailability. The compound's intricate structure indicates potential for specific interactions with biological targets, which may be relevant in drug design or therapeutic contexts. Its synthesis and characterization would typically involve standard organic chemistry techniques, and its stability, solubility, and reactivity would be influenced by the functional groups present. Overall, this compound exemplifies the complexity often found in biologically active molecules.

Formula: C₂₃H₂₉N₇O₆ClH

Synonyms:

• Benzenepropanoicacid, 4-[2-[[6-amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]-, monohydrochloride(9CI)
• CGS 21680 hydrochloride
• Cgs 21680A

Benzenepropanoic acid, 4-[2-[[6-amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]-, hydrochloride (1:1)

CAS: 124431-80-7

Formula: C₂₃H₃₀ClN₇O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 535.9806

Ref: IN-DA000M0V

CGS 21680 Hydrochloride

CAS: 124431-80-7

CGS 21680 Hydrochloride

Purity: ≥95%

Molecular weight: 535.98g/mol

Ref: 54-BUP02981

CGS 21680A

CAS: 124431-80-7

Ref: 7W-GC8846

3-(4-(2-((6-Amino-9-((2R,3R,4S,5S)-5-(Ethylcarbamoyl)-3,4-Dihydroxytetrahydrofuran-2-Yl)-9H-Purin-2-Yl)Amino)Ethyl)Phenyl)Propanoic Acid Hydrochloride

CAS: 124431-80-7

3-(4-(2-((6-Amino-9-((2R,3R,4S,5S)-5-(Ethylcarbamoyl)-3,4-Dihydroxytetrahydrofuran-2-Yl)-9H-Purin-2-Yl)Amino)Ethyl)Phenyl)Propanoic Acid Hydrochloride

Purity: 98%

Molecular weight: 535.98g/mol

Ref: 54-OR1023080

CGS 21680 Hydrochloride

CAS: 124431-80-7

Formula: C₂₃H₂₉N₇O₆·HCl

Purity: >95.0%(HPLC)(qNMR)

Color and Shape: White to Light yellow powder to lump

Molecular weight: 535.99

Ref: 3B-C3908

CGS 21680 Hydrochloride

CAS: 124431-80-7

CGS 21680 Hydrochloride (CGS 21680 HCl)(IC50=22 nM), an adenosine receptor agonist, exhibits 140-fold potency in A2 receptor over A1 receptor.

Formula: C₂₃H₂₉N₇O₆·HCl

Purity: 96.74% - 99.53%

Color and Shape: Solid

Molecular weight: 535.98

Ref: TM-T6441

CGS 21680A

Controlled Product

CAS: 124431-80-7

Applications Adenosine receptors are related to many diseases such as cardiovascular, autoimmune, and cancer. CGS 21680 is a potent and selective agonist of the adenosine A2A receptor, a member of G protein coupled receptor (1,2,3).
References (1) Jones, K. R., et al.: Sci Rep. 7, 44816 (2017) (2) Hutchison, A. J., et al.: J. Pharm. Exp. Ther. 251, 47 (1989) (3) Hasko, G., et al.: Nat. Rev. Drug Discov. 7, 759 (2008)

Formula: C₂₃H₂₉N₇O₆·ClH

Color and Shape: Neat

Molecular weight: 535.98

Ref: TR-C291790

CGS 21680 HCl

CAS: 124431-80-7

Selective A2 adenosine receptor agonist. Increases cardiac output in rats with acute heart failure, mediated by reduced venous resistance and raised heart rate. Demonstrates neuroprotective properties by lowering blood cell infiltrates and neuroinflammation in ischemic cerebral tissue.

Formula: C₂₃H₃₀ClN₇O₆

Purity: Min. 95%

Color and Shape: White to off-white solid.

Molecular weight: 535.98 g/mol

Ref: 3D-NC16650