CAS 124505-87-9

(2S)-2-amino-6-[8-[[(4S)-4-amino-4-carboxy-butyl]amino]-2,7,9-triazabicyclo[4.3.0]nona-3,5,7,9-tetraen-2-yl]hexanoic acid

Description:

The chemical substance known as (2S)-2-amino-6-[8-[[(4S)-4-amino-4-carboxy-butyl]amino]-2,7,9-triazabicyclo[4.3.0]nona-3,5,7,9-tetraen-2-yl]hexanoic acid, with the CAS number 124505-87-9, is a complex organic compound characterized by its multi-functional structure, which includes amino and carboxylic acid groups. This compound features a bicyclic triazole moiety, contributing to its potential biological activity. The presence of multiple amino groups suggests that it may participate in various biochemical interactions, possibly acting as a ligand or a substrate in enzymatic reactions. Its hexanoic acid chain provides hydrophobic characteristics, which may influence its solubility and membrane permeability. The stereochemistry indicated by the (2S) and (4S) designations suggests specific spatial arrangements that could be crucial for its biological function. Overall, this compound's intricate structure and functional groups may render it of interest in medicinal chemistry and biochemistry, particularly in the development of pharmaceuticals or as a research tool in studying biological processes.

Formula: C₁₇H₂₆N₆O₄

InChI: InChI=1S/C17H26N6O4/c18-11(15(24)25)5-1-2-9-23-10-4-7-13-14(23)22-17(21-13)20-8-3-6-12(19)16(26)27/h4,7,10-12H,1-3,5-6,8-9,18-19H2,(H,20,21)(H,24,25)(H,26,27)/t11-,12-/m0/s1

InChI key: InChIKey=AYEKKSTZQYEZPU-RYUDHWBXSA-N

SMILES: C(CCC[C@@H](C(O)=O)N)N1C=2C(N=C(NCCC[C@@H](C(O)=O)N)N2)=CC=C1

Synonyms:

• (αS)-α-Amino-2-[[(4S)-4-amino-4-carboxybutyl]amino]-4H-imidazo[4,5-b]pyridine-4-hexanoic acid
• 4H-Imidazo[4,5-b]pyridine-4-hexanoic acid, α-amino-2-[(4-amino-4-carboxybutyl)amino]-, [S-(R*,R*)]-
• 4H-Imidazo[4,5-b]pyridine-4-hexanoic acid, α-amino-2-[[(4S)-4-amino-4-carboxybutyl]amino]-, (αS)-
• 6-(2-{[(4S)-4-amino-4-carboxybutyl]amino}-4H-imidazo[4,5-b]pyridin-4-yl)-L-norleucine
• Pentosidine
• Pentosidine. TFA salt

4H-Imidazo[4,5-b]pyridine-4-hexanoic acid, α-amino-2-[[(4S)-4-amino-4-carboxybutyl]amino]-, (αS)-

CAS: 124505-87-9

Formula: C₁₇H₂₆N₆O₄

Molecular weight: 378.4261

Ref: IN-DA000M4Y

Pentosidine

CAS: 124505-87-9

AGEs are non-enzymatic products from sugar-protein/lipid reactions linked to various diseases and aging; RAGE receptors initiate signaling.

Formula: C₁₇H₂₆N₆O₄

Color and Shape: Solid

Molecular weight: 378.433

Ref: TM-T35890

Pentosidine trifluoroacetate salt

CAS: 124505-87-9

Pentosidine trifluoroacetate salt

Formula: C₁₇H₂₆N₆O₄·C₂HF₃O₂

Purity: 99.8% (hplc) (Typical Value in Batch COA)

Color and Shape: Solid

Molecular weight: 492.45g/mol

Ref: 54-BIP0243

Pentosidine

CAS: 124505-87-9

Formula: C₁₇H₂₆N₆O₄

Molecular weight: 378.43

Ref: 4Z-P-350001

Pentosidine-d3 Trifluoroacetic Acid Salt

Controlled Product

CAS: 124505-87-9

Stability Hygroscopic
Applications A biochemical marker of bone turnover for management of metabolic bone diseases.
References Turner, W., et al.: Biol. Psychiatry, 14, 177 (1979), Miyata, T., et al.: Kidney Int., 60, 2351 (2001), Politi, P., et al.: Neurosci. Lett., 396, 163 (2006),

Formula: C₁₇H₂₃D₃N₆O₄·x(C₂HF₃O₂)

Color and Shape: Neat

Molecular weight: 381.44 + x(114.02)

Ref: TR-P276302

Pentosidine-d4 Trifluoroacetic Acid Salt

Controlled Product

CAS: 124505-87-9, 225784-09-8

Formula: C₁₇H₂₂D₄N₆O₄•x(C₂HF₃O₂)

Color and Shape: Neat

Molecular weight: 382.45 + x(114.02)

Ref: TR-P276301

Pentosidine Trifluoroacetic Acid Salt

Controlled Product

CAS: 124505-87-9, 225784-09-8, 360560-46-9

Formula: C₁₇H₂₆N₆O₄•x(C₂HF₃O₂)

Color and Shape: Neat

Molecular weight: 378.43 + x(114.02)

Ref: TR-P276300

Pentosidine

CAS: 124505-87-9

A Pentosidine product which can be used as a biomarker for Advanced Glycation End Products (known as AGEs) and for Glycation-Oxidative stress which is seen in diabetes mellitus type 2. It is available in the Trifluoroacetate Salt form and as a 0.1mg vial.

Formula: C₁₇H₂₆N₆O₄

Purity: Min. 95%

Molecular weight: 378.43 g/mol

Ref: 3D-SAE-3242-V