CAS 1245555-42-3
:Afatinib Impurity 19
Description:
Afatinib Impurity 19, with the CAS number 1245555-42-3, is a chemical compound associated with the pharmaceutical drug Afatinib, which is used primarily in the treatment of non-small cell lung cancer. As an impurity, it is typically a byproduct of the synthesis of Afatinib and may not possess the same therapeutic properties. The characteristics of this impurity can include its molecular structure, which may differ slightly from the parent compound, affecting its physical and chemical properties such as solubility, stability, and reactivity. Impurities like Afatinib Impurity 19 are often analyzed for their potential impact on the efficacy and safety of the final drug product. Regulatory agencies require detailed characterization of such impurities to ensure quality control in pharmaceutical manufacturing. Analytical techniques such as HPLC, NMR, and mass spectrometry are commonly employed to identify and quantify impurities in drug substances. Understanding the characteristics of impurities is crucial for maintaining the integrity of pharmaceutical formulations and ensuring patient safety.
Formula:C21H21ClFN5O2
Synonyms:- 7-(((3-chloro-4-fluorophenyl)amino)methyl)-6-nitroquinazolin-4-ol
- Afatinib Impurity 19
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