CAS 1245603-92-2

N,N-dimethyl-5-((2-methyl-6-((5-methylpyrazin-2-yl)carbamoyl)benzofuran-4-yl)oxy)pyrimidine-2-carboxamide

Description:

N,N-Dimethyl-5-((2-methyl-6-((5-methylpyrazin-2-yl)carbamoyl)benzofuran-4-yl)oxy)pyrimidine-2-carboxamide, identified by CAS number 1245603-92-2, is a synthetic organic compound characterized by its complex molecular structure, which includes a pyrimidine ring, a benzofuran moiety, and a pyrazine derivative. This compound features multiple functional groups, including amide and ether linkages, contributing to its potential biological activity. The presence of dimethyl groups suggests enhanced lipophilicity, which may influence its pharmacokinetic properties. The compound's design indicates potential applications in medicinal chemistry, particularly in drug development, where it may exhibit specific interactions with biological targets. Its structural complexity may also suggest unique properties in terms of solubility and stability. As with many synthetic compounds, further studies would be necessary to fully elucidate its chemical behavior, biological activity, and potential therapeutic applications.

Formula: C₂₂H₂₀N₆O₄

Synonyms:

• N,N-Dimethyl-5-[[2-methyl-6-[[(5-methyl-2-pyrazinyl)amino]carbonyl]-4-benzofuranyl]oxy]-2-pyrimidinecarboxamide
• PF-04937319 >=98% (HPLC)
• N,N-dimethyl-5-((2-methyl-6-((5-methylpyrazin-2-yl)carbamoyl)benzofuran-4-yl)oxy)pyrimidine-2-carboxamide
• N,N-Dimethyl-5-[2-methyl-6-[N-(5-methylpyrazin-2-yl)carbamoyl]-1-benzofuran-4-yloxy]pyrimidine-2-carboxamide
• Inhibitor,PF-04937319,Hexokinase IV,PF 04937319,PF04937319,Hexokinase D,inhibit,Glucokinase
• 2-Pyrimidinecarboxamide, N,N-dimethyl-5-[[2-methyl-6-[[(5-methyl-2-pyrazinyl)amino]carbonyl]-4-benzofuranyl]oxy]-
• EOS-61370
• PF-04937319

Nerigliatin

CAS: 1245603-92-2

Formula: C₂₂H₂₀N₆O₄

Purity: 99.78%

Molecular weight: 432.4320

Ref: IN-DA000M7C

PF-04937319

CAS: 1245603-92-2

PF-04937319

Purity: ≥98%

Molecular weight: 432.43g/mol

Ref: 54-BUP14262

PF 04937319

CAS: 1245603-92-2

PF 04937319 is an investigative ophthalmic drug candidate, which is derived from chemical synthesis. It functions as an inhibitor of the Rho kinase enzyme. The Rho kinase pathway is critical in regulating aqueous humor outflow in the eye, and its inhibition reduces intraocular pressure, a primary risk factor for glaucoma.

Formula: C₂₂H₂₀N₆O₄

Purity: Min. 95%

Molecular weight: 432.43 g/mol

Ref: 3D-VZB60392

PF-04937319

CAS: 1245603-92-2

PF-04937319 activates glucokinase (EC50=154.4μM) with low hypoglycemia risk, researched for type 2 diabetes treatment.

Formula: C₂₂H₂₀N₆O₄

Purity: 99.89%

Color and Shape: Solid

Molecular weight: 432.43

Ref: TM-T16479