CAS 1246213-24-0

2-(5-(tert-Butyl)-2-hydroxy-4-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl)-2-methylpropanoic acid

CAS: 1246213-24-0

Formula: C₂₄H₂₆N₂O₅

Color and Shape: Solid

Molecular weight: 422.4736

Ref: IN-DA000MH0

Ivacaftor Impurity 1

CAS: 1246213-24-0

Formula: C₂₄H₂₆N₂O₅

Molecular weight: 422.49

Ref: 4Z-I-056004

Ivacaftor Carboxylic Acid

CAS: 1246213-24-0

Formula: C₂₄H₂₆N₂O₅

Molecular weight: 422.47

Ref: ST-EA-CP-I12001

Ivacaftor Carboxylic Acid

CAS: 1246213-24-0

Applications Ivacaftor Carboxylic Acid is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.
References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)

Formula: C₂₄H₂₆N₂O₅

Color and Shape: Neat

Molecular weight: 422.47

Ref: TR-I940605

Ivacaftor carboxylic acid

CAS: 1246213-24-0

Ivacaftor carboxylic acid is a pharmaceutical drug that is used to treat cystic fibrosis. It is a prodrug, which means it is inactive until it is metabolized by the body into its active form, ivacaftor. Ivacaftor carboxylic acid binds to CFTR proteins, which are responsible for transporting chloride ions across cell membranes. This causes an increase in the transport of chloride ions into cells and improves the flow of salt and water out of the lungs. Ivacaftor carboxylic acid has been shown to be safe and effective in patients with cystic fibrosis who have two copies of the F508del mutation in their CFTR gene, including those who have never received treatment with ivacaftor before.

Formula: C₂₄H₂₆N₂O₅

Purity: Min. 95%

Molecular weight: 422.5 g/mol

Ref: 3D-WZB21324