CAS 1246253-05-3

(2R,3aR,6aR)-

Description:

The chemical substance with the name "(2R,3aR,6aR)-" and CAS number "1246253-05-3" is a specific stereoisomer, indicating its three-dimensional arrangement of atoms. This compound is characterized by its chiral centers, which contribute to its unique spatial configuration and potentially distinct biological activity compared to other isomers. The presence of multiple stereocenters suggests that it may exhibit specific interactions with biological targets, making it of interest in pharmaceutical applications. Additionally, the compound's physical properties, such as solubility, melting point, and reactivity, can vary significantly based on its stereochemistry. Understanding these characteristics is crucial for its synthesis, formulation, and potential therapeutic uses. As with many organic compounds, the stability and reactivity can also be influenced by environmental factors such as pH and temperature. Overall, the stereochemical designation and CAS number provide essential information for researchers and chemists working with this specific compound in various applications, including drug development and chemical synthesis.

Formula: C₂₃H₃₂N₂O₅

Synonyms:

• RaMipril IMpurity-J (EP)
• Ramipril Impurity 10(Ramipril EP Impurity J)
• Ramipril EP Impurity J (Ramipril Enantiomer)
• ent-RaMipril
• (2R,3aR,6aR)-
• (2R,3aR,6aR)-1-[(2R)-2-[[(2R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid

Ramipril EP Impurity J (Ramipril Enantiomer)

CAS: 1246253-05-3

Formula: C₂₃H₃₂N₂O₅

Color and Shape: White To Off-White Solid

Molecular weight: 416.52

Ref: 4Z-R-0213

ent-Ramipril

Controlled Product

CAS: 1246253-05-3

Applications ent-Ramipril is the RRRRR-isomer of the antihypertensive drug Ramipril (R111000(P)). Ramipril impurity J.
References Teetz, V., et al.: Arzneim.-Forsch., 34, 1399 (1984); Ruggenenti, P., et al.: Lancet, 352, (1998); Bosch, J., et al.: Br. Med. J., 324, 1 (2002)

Formula: C₂₃H₃₂N₂O₅

Color and Shape: Neat

Molecular weight: 416.51

Ref: TR-R110990

ent-Ramipril

CAS: 1246253-05-3

Ent-ramipril is a natural product that is a metabolite of ramipril. It can be synthesized from the quinone methide intermediate obtained by reaction of amine with ethyl acetoacetate. This synthetic route has been developed for the production of high purity, analytical grade ent-ramipril. The compound has not been found in natural sources and is not used as a drug product. Ent-ramipril is not an impurity standard, but it can be used as a research and development or HPLC standard.

Formula: C₂₃H₃₂N₂O₅

Purity: Min. 95%

Molecular weight: 416.50 g/mol

Ref: 3D-WZB25305

Ramipril EP Impurity J

CAS: 1246253-05-3

Formula: C₂₃H₃₂N₂O₅

Molecular weight: 416.52

Ref: ST-EA-CP-R7013