CAS 1246298-63-4

MPLA (synthetic) Sterile Solution

CAS: 1246298-63-4

Formula: C₉₆H₁₈₇N₄O₂₂P

Purity: 99%

Molecular weight: 1780.4993

Ref: IN-DA009HGT

Lipid A monophosphoryl

CAS: 1246298-63-4

Ref: 7W-GC4240

Monophosphoryl lipid A

CAS: 1246298-63-4

MPLA, a toll-like receptor 4 agonist from nonpathogenic Salmonella, aids vaccine research.

Formula: C₉₆H₁₈₄N₃O₂₂P

Color and Shape: Solid

Molecular weight: 1763.501

Ref: TM-T38636

Lipid A monophosphoryl

CAS: 1246298-63-4

Lipid A monophosphoryl (MPL) is an adjuvant that stimulates the immune response to vaccines so that optimal protection can be achieved. MPL immunostimulant, a monophosphoryllipid A preparation derived from the lipopolysaccharide (LPS) of Salmonella minnesota R595. MPL is being considered as an adjuvant for a number of human vaccines, and experience to date has shown that it is safe, well tolerated, and able to provide a heightened immune response to coadministered antigens.

Formula: C₉₆H₁₈₁N₂O₂₂P

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 1,746.44 g/mol

Ref: 3D-OL29175

Lipid A (E. Coli) triethylammonium salt

CAS: 1246298-63-4

The Lipid A moiety of lipopolysaccharide forms the outer monolayer of the outer membrane in most Gram-negative bacteria. Escherichia coli lipid A is synthesized on the cytoplasmic side of the inner membrane by a conserved pathway of nine constitutive enzymes. Following attachment of the core oligosaccharide, nascent core-lipid A is flipped to the outer surface of the inner membrane by the ABC transporter MsbA, where the O-antigen polymer is attached. These complex glycoforms protect bacteria from antibiotics and complement-mediated lysis. The core and O-antigen domains are required for virulence and consequently are present in most clinical and environmental isolates (Raetz, 2007).

Formula: C₉₄H₁₇₈N₂O₂₅P₂

Purity: Min. 95%

Molecular weight: 1,798.37 g/mol

Ref: 3D-OL58744