CAS 1246343-36-1

Praziquantel-d11

Description:

Praziquantel-d11 is a deuterated form of praziquantel, a medication primarily used to treat parasitic infections, particularly schistosomiasis and other trematode infections. The "d11" designation indicates that this compound contains eleven deuterium atoms, which are isotopes of hydrogen that have one neutron, making them heavier than regular hydrogen. This deuteration can be useful in research applications, particularly in pharmacokinetics and metabolic studies, as it allows for the tracking of the compound's behavior in biological systems without interference from the natural abundance of hydrogen. Praziquantel itself works by causing severe spasms and paralysis of the worms, leading to their dislodgment from the blood vessels and subsequent elimination from the body. The chemical structure of praziquantel-d11 retains the essential characteristics of the parent compound, including its efficacy against specific parasites, while the deuterium substitution may alter certain physical and chemical properties, such as solubility and stability. Overall, praziquantel-d11 serves as a valuable tool in both clinical and research settings.

Formula: C₁₉H₂₄N₂O₂

Synonyms:

• 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-(pyrazino-d11)[2,1-a]isoquinolin-4-one
• Droncit-d11
• Praziquantel-d11
• 2-(Cyclohexyl-d11-carbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one
• Pyquiton-d11
• Praziquantel-(cyclohexyl-d11)
• Azinox-d11
• EMbay 8440-d11
• 4H-Pyrazino[2,1-a]isoquinolin-4-one, 2-(cyclohexyl-d11-carbonyl)-1,2,3,6,7,11b-hexahydro-
• [2H11]-Praziquantel
• Distocide-d11
• Praziquantel-d11 ((S)-Praziquantel-d11 & (R)-Praziquantel-d11 also available)
• Prazinon-d11
• Biltricide-d11
• Cesol-d11
• Cysticide-d11
• 2-(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one

Praziquantel-d11

CAS: 1246343-36-1

Formula: C₁₉H₁₃D₁₁N₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 323.48

Ref: 4Z-P-632

Praziquantel-d11

Controlled Product

CAS: 1246343-36-1

Applications Labelled Praziquantel (P702095). Anthelmintic, effective against flatworms.
References Kuhn, I., et al.: Bioorg. Med. Chem., 18, 7900 (2010), Wang, W., et al.: Parasitol., 137, 1905 (2010),

Formula: C₁₉₂H₁₁H₁₃N₂O₂

Color and Shape: White To Light Beige

Molecular weight: 323.47

Ref: TR-P702097

Praziquantel D11

CAS: 1246343-36-1

Praziquantel D11 is the deuterium labeled Praziquantel, and is an agent of anthelmintic.

Formula: C₁₉H₂₄N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 323.47

Ref: TM-T19527