CAS 1246814-92-5

Hydroxy Urea-13C-15N2

CAS: 1246814-92-5

Formula: CH₄₁₅N₂O₂

Molecular weight: 79.03

Ref: 4Z-U-062

Hydroxy Urea-13C,15N2

Controlled Product

CAS: 1246814-92-5

Applications Labelled Hydroxyurea. An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.
References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),

Formula: CH₄N₂O₂

Color and Shape: Off White Solid

Molecular weight: 79.03

Ref: TR-H991002