CAS 1246815-50-8

Mazindol-d4

Description:

Mazindol-d4 is a deuterated form of mazindol, a compound primarily known for its use as an appetite suppressant and potential treatment for attention deficit hyperactivity disorder (ADHD). The "d4" designation indicates that four hydrogen atoms in the mazindol molecule have been replaced with deuterium, a stable isotope of hydrogen. This modification can enhance the compound's stability and alter its pharmacokinetic properties, making it useful in research applications, particularly in studies involving metabolic pathways and drug interactions. Mazindol itself functions as a central nervous system stimulant, affecting neurotransmitter levels, particularly norepinephrine and dopamine. The deuterated version may be employed in various analytical techniques, such as nuclear magnetic resonance (NMR) spectroscopy, to provide clearer insights into molecular behavior and interactions. As with any chemical substance, safety and handling precautions should be observed, and its use should comply with relevant regulations and guidelines.

Formula: C₁₆H₁₃ClN₂O

Synonyms:

• 5-(4-chlorophenyl)-2,2,3,3-tetradeuterioimidazo[1,2-b]isoindol-5-ol
• [2H4]-Mazindol
• Mazindol-d4

Mazindol-D4

Controlled Product

CAS: 1246815-50-8

Applications Labelled Mazindol (M198500). Clinical trials as appetite depressant. Anorexic; CNS stimulant. Controlled substance (stimulant).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sirtori, C., et al.: Am. J. Med. Sci., 261, 341 (1971), Hadler, A.J., et al.: J. Clin. Pharmacol., 12, 453 (1972), Thompson, D.A., et al.: Metabolism., 30, 1015 (1981),

Formula: C₁₆H₉ClD₄N₂O

Color and Shape: White To Off-White

Molecular weight: 288.80

Ref: TR-M198502

Mazindol-d4 (1 mg/ml in Acetonitrile)

Controlled Product

CAS: 1246815-50-8

Formula: C₁₆H₉ClD₄N₂O

Color and Shape: Single Solution

Molecular weight: 288.80

Ref: TR-KIT5540

Mazindol-d4

Controlled Product

CAS: 1246815-50-8

Mazindol-d4 is a synthetic analogue of the endogenous peptide hormones, hydroxylase. It is a potent inhibitor of dopamine uptake and has been shown to be useful in the detection of dopamine. Mazindol-d4 has high affinity for the dopamine uptake system, which leads to its competitive inhibition of the uptake of dopamine. The ligation of mazindol-d4 to l-amino acid conjugates makes it possible for this substance to be detected by adsorption isotherm. Mazindol-d4 also binds with receptors on dopaminergic neurons and can modify their activity, which may result in an increased production of dopamine.

Formula: C₁₆H₁₃ClN₂O

Purity: Min. 95%

Molecular weight: 288.76 g/mol

Ref: 3D-WZB81550