CAS 1246817-56-0

Tizoxanide-d4

Description:

Tizoxanide-d4 is a deuterated form of tizoxanide, which is an active metabolite of the antiparasitic drug nitazoxanide. As a deuterated compound, Tizoxanide-d4 contains deuterium atoms, which are isotopes of hydrogen, replacing some of the hydrogen atoms in the molecule. This modification can enhance the stability and metabolic tracking of the compound in various studies. Tizoxanide itself is known for its broad-spectrum activity against protozoan parasites and certain viral infections, functioning primarily through the inhibition of pyruvate ferredoxin oxidoreductase, an enzyme critical for anaerobic energy metabolism in these pathogens. The deuterated version is often utilized in pharmacokinetic studies and research to better understand the drug's behavior in biological systems. Its chemical structure, while similar to that of tizoxanide, will exhibit distinct physical and chemical properties due to the presence of deuterium, which can affect its solubility, stability, and interaction with biological molecules.

Formula: C₁₀H₇N₃O₄S

Synonyms:

• [2H4]-Tizoxanide
• 2-Hydroxy-N-(5-nitro-2-thiazolyl)benzaMide-d4
• Tizoxanide D4 Q: What is the storage condition of
• NSC 697856-d4
• Tizoxanide-d4
• Tizoxanide D4Q: What is
• Tizoxanide D4
• TIZ-d4
• 2,3,4,5-tetradeuterio-6-hydroxy-N-(5-nitro-1,3-thiazol-2-yl)benzamide
• Tizoxanide D4 Q: What are the applications of
• Tizoxanide D4 Q: What is the CAS Number of

Tizoxanide-d4 (Nitazoxanide USP Related Compound B-d4)

CAS: 1246817-56-0

Formula: C₁₀H₃D₄N₃O₄S

Color and Shape: Yellow Solid

Molecular weight: 269.27

Ref: 4Z-T-442

Tizoxanide-d4

Controlled Product

CAS: 1246817-56-0

Applications A labelled metabolite of Nitazoxanide (N490100); a potent inhibitor of hepatitis B virus and hepatitis C virus. Kills Mycobacterium tuberculosis.
References Allen, M., et al.: Hepatology, 27, 1670 (1998), Blight, K., et al.: Science, 290, 1972 (2000), Blight, K., et al.: J. Virol., 77, 3181 (2003), Courcambeck, J., et al.: Antivir Ther., 11, 847 (2006), Hoffman, P., et al.: Antimicrob. Agents Chemother., 51, 868 (2007); de Carvalho et. al., J. Med. Chem., 52, 5789 (2009)

Formula: C₁₀H₃D₄N₃O₄S

Color and Shape: Neat

Molecular weight: 269.27

Ref: TR-T450102

Tizoxanide-d4

CAS: 1246817-56-0

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Formula: C₁₀H₈N₃O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 270.28 g/mol

Ref: 3D-WZB81756