CAS 1246818-67-6
:Dihydroxy Etravirine
Description:
Dihydroxy Etravirine, identified by its CAS number 1246818-67-6, is a synthetic compound that belongs to the class of non-nucleoside reverse transcriptase inhibitors (NNRTIs). It is primarily used in the treatment of HIV infection, functioning by inhibiting the reverse transcriptase enzyme, which is crucial for viral replication. The compound features two hydroxyl (-OH) groups, which contribute to its solubility and interaction with biological targets. Dihydroxy Etravirine exhibits a complex molecular structure that enhances its efficacy against HIV strains resistant to other NNRTIs. Its pharmacokinetic properties include oral bioavailability and a relatively long half-life, allowing for convenient dosing regimens. Additionally, it is characterized by its ability to penetrate the central nervous system, which is significant for treating HIV-associated neurological complications. Safety and efficacy profiles are established through clinical trials, and like other antiretroviral agents, it may have potential side effects, necessitating monitoring during therapy. Overall, Dihydroxy Etravirine represents an important advancement in HIV treatment options.
Formula:C20H15BrN6O3
Synonyms:- 4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-bis(hydroxymethyl)benzonitrile
- Dihydroxy Etravirine
- 4-[[6-AMino-5-broMo-2-[(4-cyanophenyl)aMino]-4-pyriMidinyl]oxy]-3,5-bis(hydroxyMethyl)benzonitrile
- Etravirine Dihydroxy Impurity
- Benzonitrile, 4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-bis(hydroxymethyl)-
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