CAS 1246819-36-2

2-Desethoxy-2-hydroxy-1H-1-Ethyl Candesartan Cilexetil-d5

Description:

2-Desethoxy-2-hydroxy-1H-1-Ethyl Candesartan Cilexetil-d5 is a deuterated derivative of candesartan cilexetil, which is an angiotensin II receptor antagonist used primarily in the treatment of hypertension and heart failure. This compound features a modified structure that includes deuterium atoms, which are heavier isotopes of hydrogen, enhancing its stability and allowing for more precise tracking in pharmacokinetic studies. The presence of the ethyl group and the hydroxy functional group contributes to its biological activity and solubility characteristics. As a pharmaceutical compound, it is typically characterized by its molecular weight, solubility in various solvents, and specific interactions with biological targets. The deuteration can also influence its metabolic pathways, making it useful in research to study the drug's behavior in biological systems. Overall, this compound exemplifies the application of isotopic labeling in drug development and pharmacological research.

Formula: C₃₃H₃₄N₆O₆

InChI: InChI=1S/C33H34N6O6/c1-3-39-30(35-36-37-39)26-13-8-7-12-25(26)23-18-16-22(17-19-23)20-38-29-27(14-9-15-28(29)34-32(38)41)31(40)43-21(2)44-33(42)45-24-10-5-4-6-11-24/h7-9,12-19,21,24H,3-6,10-11,20H2,1-2H3,(H,34,41)/i1D3,3D2

InChI key: InChIKey=DEGBAMTUFHKMQR-WNWXXORZSA-N

SMILES: C(N1C=2C(NC1=O)=CC=CC2C(OC(OC(OC3CCCCC3)=O)C)=O)C4=CC=C(C=C4)C5=C(C=CC=C5)C=6N(C(C([2H])([2H])[2H])([2H])[2H])N=NN6

Synonyms:

• 2-Hydroxy-1-[[2'-(1-ethyl-1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-1H-benziMidazole-7-carboxylic Acid 1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl Ester-d5
• 2-Desethoxy-2-hydroxy-1H-1-Ethyl Candesartan Cilexetil-d5
• 1-Cyclohexyloxycarbonyloxyethyl 2-hydroxy-3-[[4-[2-[1-(1,1,2,2,2-pentadeuterioethyl)tetrazol-5-yl]phenyl]phenyl]methyl]benzimidazole-4-carboxylate

2-Desethoxy-2-hydroxy-1H-1-Ethyl Candesartan Cilexetil-d5

Controlled Product

CAS: 1246819-36-2

Applications Labelled Candesartan Cilexetil impurity.
References Gohlke, P., et al.: Drugs Today, 35, 105 (1999), Michihiro, Y., et al.: Clin. Pharmacol., 93, 175 (2000), Rao, D., et al.: Chromatographia, 66, 499 (2007),

Formula: C₃₃H₂₉D₅N₆O₆

Color and Shape: White

Molecular weight: 615.69

Ref: TR-D288752

2-Desethoxy-2-hydroxy-1H-1-ethyl candesartan cilexetil-d5

CAS: 1246819-36-2

Please enquire for more information about 2-Desethoxy-2-hydroxy-1H-1-ethyl candesartan cilexetil-d5 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₃₃H₃₄N₆O₆

Purity: Min. 95%

Molecular weight: 615.7 g/mol

Ref: 3D-WZB81936