CAS 1246820-85-8

Sotalol D6 HCl

Description:

Sotalol D6 HCl is a deuterated form of the antiarrhythmic drug sotalol, which is primarily used to treat certain types of irregular heartbeats. The "D6" designation indicates that the compound contains six deuterium atoms, which are isotopes of hydrogen, replacing the regular hydrogen atoms in the molecular structure. This modification can enhance the stability and tracking of the compound in various studies, particularly in pharmacokinetics and metabolic research. Sotalol itself is a racemic mixture, and its mechanism of action involves blocking beta-adrenergic receptors, which helps to regulate heart rhythm. The hydrochloride (HCl) component indicates that the substance is in its salt form, which is often used to improve solubility and stability. As a chemical entity, Sotalol D6 HCl would exhibit similar pharmacological properties to its non-deuterated counterpart, but the presence of deuterium may influence its metabolic pathways and interactions in biological systems. Safety and handling protocols should be observed, as with any pharmaceutical compound.

Formula: C₁₂H₁₅ClD₆N₂O₃S

Synonyms:

• (±)-Sotalol-d6 hydrochloride (dimethyl-d6)
• [2H6]- Sotalol Hydrochloride
• [2H6]-Sotalol HCl
• Sotalol D6 HCl

Sotalol hydrochloride D6 100 µg/mL in Water

Controlled Product

CAS: 1246820-85-8

Formula: C₁₂H₆H₁₄N₂O₃S·ClH

Color and Shape: Single Solution

Molecular weight: 314.86

Ref: 04-XA16972631WA

Sotalol-d6 Hydrochloride

Controlled Product

CAS: 1246820-85-8

Applications A labelled potent α-adrenergic receptor antagonist. A class III antiarrythmic. It has been shown to prolong action potential and increases the refractory period.
References Uloth, et al.: J. Med. Chem., 9, 88 (1966), Groh, W.J., et al.: Chirality, 5, 8 (1993), Pasnani, J.S., et al.: J. Pharmacol. Exp. Ther., 271, 184 (1994),

Formula: C₁₂₂H₆H₁₄N₂O₃S·ClH

Color and Shape: Off-White To Light Beige

Molecular weight: 314.86

Ref: TR-S677302