CAS 1246832-94-9

Olopatadine-d3 N-Oxide

Description:

Olopatadine-d3 N-Oxide is a deuterated derivative of olopatadine, which is an antihistamine commonly used to treat allergic conditions such as allergic rhinitis and conjunctivitis. The "d3" designation indicates that the compound contains three deuterium atoms, which are isotopes of hydrogen, enhancing its stability and allowing for specific applications in research, particularly in pharmacokinetics and metabolic studies. The N-oxide form suggests that the nitrogen atom in the olopatadine structure has been oxidized, which may influence its pharmacological properties and metabolic pathways. Generally, compounds like Olopatadine-d3 N-Oxide are characterized by their ability to inhibit histamine receptors, thereby reducing allergic symptoms. Its chemical structure includes a central benzene ring, a piperidine moiety, and various functional groups that contribute to its activity. The presence of deuterium can also aid in tracing the compound's behavior in biological systems. As with any chemical substance, safety data and handling precautions should be considered when working with Olopatadine-d3 N-Oxide in laboratory settings.

Formula: C₂₁H₂₃NO₄

Synonyms:

• Olopatadine Impurity 26
• 11-[3-(DiMethyloxidoaMino-d3)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic Acid
• Olopatadine-d3 N-Oxide

Olopatadine-d3 N-Oxide

Controlled Product

CAS: 1246832-94-9

Applications A labelled metabolite of Olopatadine (M3). A dibenz[b,e]oxepin derivative as antiallergic agents, useful for treatment of asthma, allergic rhinitis, atopic dermatitis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mizuno, N., et al.: Drug Metabol. Pharmacokin., 17, 93 (2002), Polli, J., et al.: J. Pharm. Sci., 92, 2082 (2003), Tashiro, M., et al.: J. Clin. Pharmacol., 44, 890 (2004), Ohashi, R., et al.: Drug Metab. Disos., 34, 793 (2006),

Formula: C₂₁H₂₀D₃NO₄

Color and Shape: Neat

Molecular weight: 356.43

Ref: TR-O575012