CAS 1247-64-9

Pregnenolone sulfate

Description:

Pregnenolone sulfate is a naturally occurring steroid sulfate derived from pregnenolone, which is a precursor to various steroid hormones. It is characterized by its sulfate ester functional group, which enhances its solubility in water compared to its parent compound. Pregnenolone sulfate plays a significant role in the central nervous system, where it is believed to modulate neurosteroid activity and influence cognitive functions. It is also involved in various physiological processes, including the regulation of mood and stress responses. The compound exhibits neuroprotective properties and has been studied for its potential therapeutic effects in conditions such as depression and anxiety. Pregnenolone sulfate is typically found in low concentrations in the human body and can be synthesized from pregnenolone through sulfation. Its chemical structure includes a steroid backbone with a sulfate group, which contributes to its biological activity and interaction with steroid receptors. As a research chemical, it is of interest in pharmacology and neurobiology for its diverse effects on the nervous system and hormonal balance.

Formula: C₂₁H₃₂O₅S

InChI: InChI=1S/C21H32O5S/c1-13(22)17-6-7-18-16-5-4-14-12-15(26-27(23,24)25)8-10-20(14,2)19(16)9-11-21(17,18)3/h4,15-19H,5-12H2,1-3H3,(H,23,24,25)/t15-,16-,17+,18-,19-,20-,21+/m0/s1

InChI key: InChIKey=DIJBBUIOWGGQOP-QGVNFLHTSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@H](C(C)=O)CC4)[H])(CC=C1C[C@@H](OS(=O)(=O)O)CC2)[H])[H]

Synonyms:

• (3Beta)-20-Oxopregn-5-En-3-Yl Hydrogen Sulfate
• (3β)-3-(Sulfooxy)pregn-5-en-20-one
• 20-Oxo-5-pregnen-3β-yl sulfate
• 3β-Hydroxy-5-pregnen-20-one monosulfate
• 3β-Hydroxypregn-5-en-20-one sulfate
• 5-Pregnen-3β-sulfate-20-one
• Pregn-5-en-20-on-3β-yl sulfuric acid
• Pregn-5-en-20-one, 3-(sulfooxy)-, (3β)-
• Pregn-5-en-20-one, 3β-hydroxy-, hydrogen sulfate
• Pregn-5-en-20-one-3β-yl sulfate
• Pregnenolone 3-sulfate
• Pregnenolone 3β-sulfate
• Pregnenolone hydrogen sulfate
• Pregnenolone monosulfate
• Pregnenolone sulfate

Pregn-5-en-20-one, 3-(sulfooxy)-, (3β)-

CAS: 1247-64-9

Formula: C₂₁H₃₂O₅S

Purity: 100%

Molecular weight: 396.5408

Ref: IN-DA000MN2

Pregnenolone monosulfate

CAS: 1247-64-9

Pregnenolone monosulfate

Purity: ≥98%

Molecular weight: 396.54g/mol

Ref: 54-BUP02269

Pregnenolone monosulfate

CAS: 1247-64-9

Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a potent nootropic steroid used in the study of neuroticism and depression.

Formula: C₂₁H₃₂O₅S

Purity: 99.46% - 99.72%

Color and Shape: Solid

Molecular weight: 396.54

Ref: TM-T12536

Pregnenolone monosulfate

CAS: 1247-64-9

Pregnenolone is a steroid hormone and neurosteroid. Pregnenolone is synthesized from cholesterol and has many physiological effects, including regulation of transcriptional activity, intracellular Ca2+ levels, locomotor activity, and the hippocampal formation. The physiological function of pregnenolone has been studied extensively in model organisms such as rodents. The most important receptor for pregnenolone is the nuclear receptor, which regulates diverse processes such as brain functions by controlling the expression of specific genes that encode proteins involved in these processes.
Pregnenolone also binds to the GABA A receptor (GABAA), which is a ligand-gated ion channel that plays an important role in regulating neuronal excitability. GABAA receptors are composed of five subunits with two different types (α or β) linked together to form hetero-pentamers. Pregnenolone binds to one of the α subunits on the GABAA receptor complex

Formula: C₂₁H₃₂O₅S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 396.5 g/mol

Ref: 3D-BAA24764