CAS 1247000-76-5

CFI-400437

Description:

CFI-400437, with the CAS number 1247000-76-5, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential therapeutic applications. It is characterized as a selective inhibitor of certain protein kinases, which play crucial roles in various cellular processes, including cell growth and division. This selectivity is significant as it may lead to reduced side effects compared to less selective inhibitors. The compound is typically studied for its efficacy in treating specific types of cancer and other diseases where aberrant kinase activity is implicated. In terms of its physical properties, CFI-400437 is expected to exhibit moderate solubility in organic solvents, with a molecular structure that includes functional groups conducive to its biological activity. As with many investigational compounds, ongoing research is essential to fully elucidate its pharmacokinetics, mechanism of action, and potential therapeutic benefits, as well as to assess its safety profile in clinical settings.

Formula: C₂₉H₂₉ClN₆O₂

Synonyms:

• CS-2656
• CFI-400437 HCl
• CFI-400437
• CFI 400437;CFI400437

5-Methoxy-3-((3-((E)-2-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)vinyl)-1H-indazol-6-yl)methylene)indolin-2-one dihydrochloride

CAS: 1247000-76-5

Formula: C₂₉H₃₀Cl₂N₆O₂

Purity: 98%

Molecular weight: 565.4935

Ref: IN-DA01V2QQ

5-Methoxy-3-((3-((E)-2-(6-(4-Methylpiperazin-1-Yl)Pyridin-3-Yl)Vinyl)-1H-Indazol-6-Yl)Methylene)Indolin-2-One Dihydrochloride

CAS: 1247000-76-5

5-Methoxy-3-((3-((E)-2-(6-(4-Methylpiperazin-1-Yl)Pyridin-3-Yl)Vinyl)-1H-Indazol-6-Yl)Methylene)Indolin-2-One Dihydrochloride

Purity: 98%

Molecular weight: 565.49g/mol

Ref: 54-OR1023225

(1E)-CFI-400437 dihydrochloride

CAS: 1247000-76-5

(1E)-CFI-400437 dihydrochloride

Purity: ≥98%

Molecular weight: 565.5g/mol

Ref: 54-BUP03721

(1E)-CFI-400437 dihydrochloride

CAS: 1247000-76-5

(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) is a selective and potent polo-like kinase 4 (PLK4) inhibitor.

Formula: C₂₉H₃₀Cl₂N₆O₂

Purity: 97.08%

Color and Shape: Solid

Molecular weight: 565.5

Ref: TM-T22288

CFI-400437

CAS: 1247000-76-5

CFI-400437 is a peptide that binds to the beta2 subunit of the nicotinic acetylcholine receptor. It has been shown to inhibit the activity of this receptor and is used as a research tool for studying the effects of nicotinic acetylcholine receptors on life science, pharmacology, and cell biology. CFI-400437 has also been shown to be a high purity inhibitor of ion channels.

Formula: C₂₉H₃₀Cl₂N₆O₂

Purity: Min. 95%

Molecular weight: 565.5 g/mol

Ref: 3D-XZB00076