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CAS 124832-26-4

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Valacyclovir

Description:
Valacyclovir is an antiviral medication primarily used to treat infections caused by certain types of viruses, including herpes simplex virus (HSV) and varicella-zoster virus (VZV). It is a prodrug of acyclovir, meaning that it is converted into acyclovir in the body, which is the active form that exerts the therapeutic effects. Valacyclovir is characterized by its ability to inhibit viral DNA synthesis, thereby preventing the replication of the virus. The substance is typically administered orally and is known for its improved bioavailability compared to acyclovir, allowing for less frequent dosing. Chemically, valacyclovir is classified as a nucleoside analog, and its structure includes a valine ester that enhances its absorption. Common side effects may include headache, nausea, and abdominal pain, while serious side effects can occur, particularly in patients with renal impairment. Valacyclovir is generally well-tolerated and is an important option in the management of herpes virus infections.
Formula:C13H20N6O4
InChI:InChI=1/C13H20N6O4/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20)/t8-/m0/s1
InChI key:InChIKey=HDOVUKNUBWVHOX-QMMMGPOBSA-N
SMILES:C(OCCOC([C@H](C(C)C)N)=O)N1C2=C(N=C1)C(=O)N=C(N)N2
Synonyms:
  • 2-[(2-Amino-6-oxo-3H-purin-9-yl)methoxy]ethyl (2S)-2-amino-3-methylbutanoate
  • 2-[(2-Amino-6-oxo-6,9-dihydro-1H-purin-9-yl)methoxy]ethyl (2S)-2-amino-3-methylbutanoate
  • 256U87
  • <span class="text-smallcaps">L</span>-VACV
  • <span class="text-smallcaps">L</span>-Valine ester with 9-[(2-hydroxyethoxy)methyl]guanine
  • <span class="text-smallcaps">L</span>-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester
  • L-Valine 2-(Guanin-9-Ylmethoxy)Ethyl Ester
  • L-Valine 2-[(2-Amino-1,6-Dihydro-6-Oxo-9H-Purin-9Yl)Methoxy]Ethyl Ester
  • L-Valine ester with 9-[(2-hydroxyethoxy)methyl]guanine；L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester (9CI)
  • ValACV
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Found 4 products.